NUP214 antibody

Catalog No. ABIN7264387

Product Details anti-NUP214 Antibody

Target: NUP214 (Nucleoporin 214kDa (NUP214))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This NUP214 antibody is un-conjugated

Application: Immunofluorescence (IF)

Characteristics: Polyclonal Antibody

Purification: Affinity purification

Immunogen: Recombinant fusion protein of human NUP214 (NP_005076.3).

Isotype: IgG

Application Details

Application Notes: IF 1:50-1:100

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for NUP214

Target: NUP214 (Nucleoporin 214kDa (NUP214))

Alternative Name: NUP214 (NUP214 Products)

Synonyms: CAN antibody, CAN/Nup214 antibody, CG3820 antibody, DCAN antibody, DNup214 antibody, Dmel\\CG3820 antibody, Nup 214 antibody, dCAN antibody, l(2)10444 antibody, nup214 antibody, NUP214 antibody, RGD1304977 antibody, BC039282 antibody, D2H9S46E antibody, CAIN antibody, D9S46E antibody, N214 antibody, p250 antibody, Nucleoporin 214kD antibody, nucleoporin 214kDa antibody, nucleoporin 214 antibody, Nup214 antibody, NUP214 antibody

Background: The nuclear pore complex is a massive structure that extends across the nuclear envelope, forming a gateway that regulates the flow of macromolecules between the nucleus and the cytoplasm. Nucleoporins are the main components of the nuclear pore complex in eukaryotic cells. This gene is a member of the FG-repeat-containing nucleoporins. The protein encoded by this gene is localized to the cytoplasmic face of the nuclear pore complex where it is required for proper cell cycle progression and nucleocytoplasmic transport. The 3' portion of this gene forms a fusion gene with the DEK gene on chromosome 6 in a t(6,9) translocation associated with acute myeloid leukemia and myelodysplastic syndrome. Alternative splicing of this gene results in multiple transcript variants encoding different isoforms.

Gene ID: 8021

UniProt: P35658

Pathways: Protein targeting to Nucleus, SARS-CoV-2 Protein Interactome, The Global Phosphorylation Landscape of SARS-CoV-2 Infection