TRIM23 antibody

Catalog No. ABIN7264355

Product Details anti-TRIM23 Antibody

Target: TRIM23 (Tripartite Motif Containing 23 (TRIM23))

Reactivity: Human, Rat, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This TRIM23 antibody is un-conjugated

Application: Western Blotting (WB)

Characteristics: Polyclonal Antibody

Purification: Affinity purification

Immunogen: Recombinant fusion protein of human TRIM23 (NP_001647.1).

Isotype: IgG

Application Details

Application Notes: WB 1:500-1:2000

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for TRIM23

Target: TRIM23 (Tripartite Motif Containing 23 (TRIM23))

Alternative Name: TRIM23 (TRIM23 Products)

Synonyms: zgc:153463 antibody, ARD1 antibody, ARFD1 antibody, RNF46 antibody, 6330516O20Rik antibody, AI450195 antibody, Arfd1 antibody, Ard1 antibody, tripartite motif containing 23 antibody, tripartite motif containing 23 S homeolog antibody, tripartite motif-containing 23 antibody, trim23 antibody, trim23.S antibody, TRIM23 antibody, Trim23 antibody

Background: The protein encoded by this gene is a member of the tripartite motif (TRIM) family. The TRIM motif includes three zinc-binding domains, a RING, a B-box type 1 and a B-box type 2, and a coiled-coil region. This protein is also a member of the ADP ribosylation factor family of guanine nucleotide-binding family of proteins. Its carboxy terminus contains an ADP-ribosylation factor domain and a guanine nucleotide binding site, while the amino terminus contains a GTPase activating protein domain which acts on the guanine nucleotide binding site. The protein localizes to lysosomes and the Golgi apparatus. It plays a role in the formation of intracellular transport vesicles, their movement from one compartment to another, and phopholipase D activation. Three alternatively spliced transcript variants for this gene have been described.

Molecular Weight:

Observed_MW: 64 kDa

Calculated_MW: 61 kDa/63 kDa/64 kDa

Gene ID: 373

UniProt: P36406