MRPS22 antibody

Catalog No. ABIN7264345

Product Details anti-MRPS22 Antibody

Target: MRPS22 (Mitochondrial Ribosomal Protein S22 (MRPS22))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This MRPS22 antibody is un-conjugated

Application: Immunohistochemistry (IHC)

Characteristics: Polyclonal Antibody

Purification: Affinity purification

Immunogen: Recombinant fusion protein of human MRPS22 (NP_064576.1).

Isotype: IgG

Application Details

Application Notes: IHC 1:50-1:100

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for MRPS22

Target: MRPS22 (Mitochondrial Ribosomal Protein S22 (MRPS22))

Alternative Name: MRPS22 (MRPS22 Products)

Synonyms: AAF56757 antibody, CG12261 antibody, Dmel\\CG12261 antibody, MRP-S22 antibody, MrpS22 antibody, C3orf5 antibody, COXPD5 antibody, GIBT antibody, RPMS22 antibody, 3100002P07Rik antibody, Rpms22 antibody, DKFZp468F2212 antibody, zgc:165596 antibody, mitochondrial ribosomal protein S22 antibody, 28S ribosomal protein S22, mitochondrial antibody, mRpS22 antibody, MRPS22 antibody, Mrps22 antibody, LOC726000 antibody, mrps22 antibody

Background: Mammalian mitochondrial ribosomal proteins are encoded by nuclear genes and help in protein synthesis within the mitochondrion. Mitochondrial ribosomes (mitoribosomes) consist of a small 28S subunit and a large 39S subunit. They have an estimated 75 % protein to rRNA composition compared to prokaryotic ribosomes, where this ratio is reversed. Another difference between mammalian mitoribosomes and prokaryotic ribosomes is that the latter contain a 5S rRNA. Among different species, the proteins comprising the mitoribosome differ greatly in sequence, and sometimes in biochemical properties, which prevents easy recognition by sequence homology. This gene encodes a 28S subunit protein that does not seem to have a counterpart in prokaryotic and fungal-mitochondrial ribosomes. This gene lies telomeric of and is transcribed in the opposite direction from the forkhead box L2 gene. A pseudogene corresponding to this gene is found on chromosome Xq.

Gene ID: 56945

UniProt: P82650