SHOX2 antibody

Catalog No. ABIN7264337

Product Details anti-SHOX2 Antibody

Target: SHOX2 (Short Stature Homeobox 2 (SHOX2))

Reactivity: Human, Rat, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This SHOX2 antibody is un-conjugated

Application: Western Blotting (WB)

Characteristics: Polyclonal Antibody

Purification: Affinity purification

Immunogen: Recombinant fusion protein of human SHOX2 (NP_003021.3).

Isotype: IgG

Application Details

Application Notes: WB 1:500-1:2000

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for SHOX2

Target: SHOX2 (Short Stature Homeobox 2 (SHOX2))

Alternative Name: SHOX2 (SHOX2 Products)

Background: This gene is a member of the homeobox family of genes that encode proteins containing a 60-amino acid residue motif that represents a DNA binding domain. Homeobox genes have been characterized extensively as transcriptional regulators involved in pattern formation in both invertebrate and vertebrate species. Several human genetic disorders are caused by aberrations in human homeobox genes. This locus represents a pseudoautosomal homeobox gene that is thought to be responsible for idiopathic short stature, and it is implicated in the short stature phenotype of Turner syndrome patients. This gene is considered to be a candidate gene for Cornelia de Lange syndrome. Alternative splicing results in multiple transcript variants.

Molecular Weight:

Observed_MW: 30 kDa

Calculated_MW: 33 kDa/34 kDa/37 kDa

Gene ID: 6474

UniProt: O60902

Pathways: Regulation of Muscle Cell Differentiation, Skeletal Muscle Fiber Development