EXOC2 antibody

Catalog No. ABIN7264281

Product Details anti-EXOC2 Antibody

Target: EXOC2 (Exocyst Complex Component 2 (EXOC2))

Reactivity: Mouse, Human, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This EXOC2 antibody is un-conjugated

Application: Western Blotting (WB), Immunofluorescence (IF)

Characteristics: Polyclonal Antibody

Purification: Affinity purification

Immunogen: Recombinant fusion protein of human EXOC2 (NP_060773.3).

Isotype: IgG

Application Details

Application Notes: WB 1:500-1:2000 IF 1:50-1:200

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for EXOC2

Target: EXOC2 (Exocyst Complex Component 2 (EXOC2))

Alternative Name: EXOC2 (EXOC2 Products)

Synonyms: CG8843 antibody, Dmel\\CG8843 antibody, Sec-5 antibody, Sec5 antibody, Sec5p antibody, dsec5 antibody, SEC5 antibody, SEC5L1 antibody, 2410030I24Rik antibody, AI648199 antibody, Sec5l1 antibody, Rsec5 antibody, F7O12.2 antibody, F7O12_2 antibody, exocyst complex component sec5 antibody, Secretory 5 antibody, exocyst complex component 2 antibody, exocyst complex component sec5 antibody, Exocyst complex component 2 antibody, Sec5 antibody, EXOC2 antibody, Exoc2 antibody, SEC5A antibody, sec-5 antibody

Background: The protein encoded by this gene is a component of the exocyst complex, a multi-protein complex essential for the polarized targeting of exocytic vesicles to specific docking sites on the plasma membrane. Though best characterized in yeast, the component proteins and the functions of the exocyst complex have been demonstrated to be highly conserved in higher eukaryotes. At least eight components of the exocyst complex, including this protein, are found to interact with the actin cytoskeletal remodeling and vesicle transport machinery. This interaction has been shown to mediate filopodia formation in fibroblasts. This protein has been shown to interact with the Ral subfamily of GTPases and thereby mediate exocytosis by tethering vesicles to the plasma membrane. Alternative splicing results in multiple transcript variants.

Molecular Weight:

Observed_MW: 108 kDa

Calculated_MW: 104 kDa

Gene ID: 55770

UniProt: Q96KP1

Pathways: Peptide Hormone Metabolism, Regulation of Actin Filament Polymerization, Synaptic Vesicle Exocytosis