IL27 Receptor alpha antibody

Catalog No. ABIN7264231

Product Details anti-IL27 Receptor alpha Antibody

Target: IL27 Receptor alpha (IL27RA) (Interleukin 27 Receptor, alpha (IL27RA))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This IL27 Receptor alpha antibody is un-conjugated

Application: Immunofluorescence (IF)

Characteristics: Polyclonal Antibody

Purification: Affinity purification

Immunogen: Recombinant fusion protein of human IL27RA (NP_004834.1).

Isotype: IgG

Application Details

Application Notes: IF 1:50-1:200

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for IL27 Receptor alpha

Target: IL27 Receptor alpha (IL27RA) (Interleukin 27 Receptor, alpha (IL27RA))

Alternative Name: IL27RA (IL27RA Products)

Synonyms: IL27RA antibody, CRL1 antibody, IL-27RA antibody, IL27R antibody, TCCR antibody, WSX1 antibody, zcytor1 antibody, IL-27R antibody, Tccr antibody, WSX-1 antibody, Wsx1 antibody, interleukin 27 receptor subunit alpha antibody, interleukin-27 receptor subunit alpha antibody, interleukin 27 receptor, alpha antibody, IL27RA antibody, LOC484907 antibody, Il27ra antibody

Background: In mice, CD4+ helper T-cells differentiate into type 1 (Th1) cells, which are critical for cell-mediated immunity, predominantly under the influence of IL12. Also, IL4 influences their differentiation into type 2 (Th2) cells, which are critical for most antibody responses. Mice deficient in these cytokines, their receptors, or associated transcription factors have impaired, but are not absent of, Th1 or Th2 immune responses. This gene encodes a protein which is similar to the mouse T-cell cytokine receptor Tccr at the amino acid level, and is predicted to be a glycosylated transmembrane protein.

Gene ID: 9466

UniProt: Q6UWB1

Pathways: Regulation of Leukocyte Mediated Immunity, Production of Molecular Mediator of Immune Response