Phospholipase C beta 2 antibody

Catalog No. ABIN7264191

Product Details anti-Phospholipase C beta 2 Antibody

Target: Phospholipase C beta 2 (PLCb2) (phospholipase C beta 2 (PLCb2))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Phospholipase C beta 2 antibody is un-conjugated

Application: Immunohistochemistry (IHC)

Characteristics: Polyclonal Antibody

Purification: Affinity purification

Immunogen: Recombinant fusion protein of human PLCB2 (NP_001271228.1).

Isotype: IgG

Application Details

Application Notes: IHC 1:50-1:100

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for Phospholipase C beta 2

Target: Phospholipase C beta 2 (PLCb2) (phospholipase C beta 2 (PLCb2))

Alternative Name: PLCB2 (PLCb2 Products)

Synonyms: AI550384 antibody, B230205M18Rik antibody, B230399N12 antibody, phospholipase C, beta 2 antibody, phospholipase C beta 2 antibody, Plcb2 antibody, PLCB2 antibody

Background: The protein encoded by this gene is a phosphodiesterase that catalyzes the hydrolysis of phosphatidylinositol 4,5-bisphosphate to the second messengers inositol 1,4,5-trisphosphate (IP3) and diacylglycerol. The encoded protein is activated by G proteins and has been shown to be involved in the type 2 taste receptor signal transduction pathway. In addition, nuclear factor kappa B can regulate the transcription of this gene, whose protein product is also an important regulator of platelet responses.

Gene ID: 5330

UniProt: Q00722

Pathways: WNT Signaling, Thyroid Hormone Synthesis, CXCR4-mediated Signaling Events, G-protein mediated Events, Thromboxane A2 Receptor Signaling