CAPZB antibody

Catalog No. ABIN7264149

Product Details anti-CAPZB Antibody

Target: CAPZB (Capping Protein (Actin Filament) Muscle Z-Line, beta (CAPZB))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This CAPZB antibody is un-conjugated

Application: Immunofluorescence (IF)

Characteristics: Polyclonal Antibody

Purification: Affinity purification

Immunogen: Recombinant fusion protein of human CAPZB (NP_004921.1).

Isotype: IgG

Application Details

Application Notes: IF 1:50-1:200

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for CAPZB

Target: CAPZB (Capping Protein (Actin Filament) Muscle Z-Line, beta (CAPZB))

Alternative Name: CAPZB (CAPZB Products)

Synonyms: CAPB antibody, CAPPB antibody, CAPZ antibody, wu:fk65f06 antibody, zgc:66149 antibody, MGC52754 antibody, capzb antibody, 1700120C01Rik antibody, AI325129 antibody, CPB1 antibody, CPB2 antibody, CPbeat2 antibody, CPbeta1 antibody, CPbeta2 antibody, Cappb1 antibody, capping actin protein of muscle Z-line beta subunit antibody, capping protein (actin filament) muscle Z-line, beta antibody, F-actin-capping protein subunit beta antibody, f-actin-capping protein subunit beta antibody, capping protein (actin filament) muscle Z-line, beta L homeolog antibody, CAPZB antibody, capzb antibody, AOR_1_1412174 antibody, MCYG_05913 antibody, VDBG_04956 antibody, MGYG_06053 antibody, PGTG_03178 antibody, Tsp_07516 antibody, capzb.L antibody, Capzb antibody

Background: This gene encodes the beta subunit of the barbed-end actin binding protein, which belongs to the F-actin capping protein family. The capping protein is a heterodimeric actin capping protein that blocks actin filament assembly and disassembly at the fast growing (barbed) filament ends and functions in regulating actin filament dynamics as well as in stabilizing actin filament lengths in muscle and nonmuscle cells. A pseudogene of this gene is located on the long arm of chromosome 2. Multiple alternatively spliced transcript variants encoding different isoforms have been found.

Gene ID: 832

UniProt: P47756

Pathways: Regulation of Actin Filament Polymerization