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TNK1 antibody (AA 581-666)

TNK1 Reactivity: Human ELISA, IF (cc), IF (p), IHC (p), IHC (fro) Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN701215
  • Target See all TNK1 Antibodies
    TNK1 (Tyrosine Kinase, Non-Receptor, 1 (TNK1))
    Binding Specificity
    • 14
    • 11
    • 8
    • 6
    • 6
    • 4
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 581-666
    Reactivity
    • 47
    • 12
    • 1
    • 1
    • 1
    • 1
    • 1
    Human
    Host
    • 49
    • 8
    Rabbit
    Clonality
    • 49
    • 8
    Polyclonal
    Conjugate
    • 17
    • 5
    • 5
    • 5
    • 4
    • 4
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This TNK1 antibody is un-conjugated
    Application
    • 36
    • 30
    • 20
    • 13
    • 13
    • 7
    • 3
    • 2
    • 1
    • 1
    ELISA, Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))
    Predicted Reactivity
    Human,Mouse,Rat,Cow,Horse
    Purification
    Purified by Protein A.
    Immunogen
    KLH conjugated synthetic peptide derived from human TNK1
    Isotype
    IgG
    Top Product
    Discover our top product TNK1 Primary Antibody
  • Application Notes
    ELISA 1:500-1000
    IHC-P 1:200-400
    IHC-F 1:100-500
    IF(IHC-P) 1:50-200
    IF(IHC-F) 1:50-200
    IF(ICC) 1:50-200
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    1 μg/μL
    Buffer
    0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.
    Preservative
    ProClin
    Precaution of Use
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
    Storage
    4 °C,-20 °C
    Storage Comment
    Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.
    Expiry Date
    12 months
  • Target
    TNK1 (Tyrosine Kinase, Non-Receptor, 1 (TNK1))
    Alternative Name
    TNK1 (TNK1 Products)
    Synonyms
    Kos1 antibody, Tnk1a antibody, Tnk1b antibody, Ack-like antibody, tyrosine kinase non receptor 1 antibody, tyrosine kinase, non-receptor, 1 antibody, TNK1 antibody, Tnk1 antibody
    Background

    Synonyms: CD38 negative kinase 1, EC 2.7.10.2 antibody Kinase of embryonic stem cells, Kos 1, Kos1, MGC46193, Non receptor tyrosine protein kinase TNK 1, Non receptor tyrosine protein kinase TNK1, Tnk 1, Tyrosine kinase non receptor 1.

    Background: Tnk1 is a nonreceptor protein tyrosine kinase (NRPTK) and a new member of the Ack family of NRPTKs. Tnk1 is a ubiquitously expressed 47- kDa protein with autotyrosine kinase activity that is developmentally regulated during embryogenesis. Tnk1 is also upregulated following IL3 withdrawal from factor-dependent murine NSF/N1.H7 cells that undergo apoptosis, suggesting a role in growth inhibition. Data support a negative regulatory role for Tnk1 in regulating the Ras-Raf1-MAPK growth pathway by a mechanism that requires its autotyrosine kinase activity.

    Gene ID
    8711
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