ARNT2 antibody

Catalog No. ABIN7264109

Product Details anti-ARNT2 Antibody

Target: ARNT2 (Aryl Hydrocarbon Receptor Nuclear Translocator 2 (ARNT2))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This ARNT2 antibody is un-conjugated

Application: Immunohistochemistry (IHC)

Characteristics: Polyclonal Antibody

Purification: Affinity purification

Immunogen: Recombinant fusion protein of human ARNT2 (NP_055677.3).

Isotype: IgG

Application Details

Application Notes: IHC 1:50-1:200

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for ARNT2

Target: ARNT2 (Aryl Hydrocarbon Receptor Nuclear Translocator 2 (ARNT2))

Alternative Name: ARNT2 (ARNT2 Products)

Synonyms: bHLHe1 antibody, Hif-2b antibody, mKIAA0307 antibody, Arnt antibody, arnt2X antibody, arnt2a antibody, chunp6921 antibody, zfARNT2 antibody, zfARNT2a antibody, zfARNT2b antibody, zfARNT2c antibody, arnt2 antibody, MGC53123 antibody, arnt.2 antibody, MGC68805 antibody, ARNT2 antibody, aryl hydrocarbon receptor nuclear translocator 2 antibody, aryl-hydrocarbon receptor nuclear translocator 2 antibody, aryl hydrocarbon receptor nuclear translocator 2 S homeolog antibody, aryl hydrocarbon receptor nuclear translocator S homeolog antibody, ARNT2 antibody, Arnt2 antibody, arnt2 antibody, arnt2.S antibody, arnt.S antibody, LOC100067423 antibody

Background: This gene encodes a member of the basic-helix-loop-helix-Per-Arnt-Sim (bHLH-PAS) superfamily of transcription factors. The encoded protein acts as a partner for several sensor proteins of the bHLH-PAS family, forming heterodimers with the sensor proteins that bind regulatory DNA sequences in genes responsive to developmental and environmental stimuli. Under hypoxic conditions, the encoded protein complexes with hypoxia-inducible factor 1alpha in the nucleus and this complex binds to hypoxia-responsive elements in enhancers and promoters of oxygen-responsive genes. A highly similar protein in mouse forms functional complexes with both aryl hydrocarbon receptors and Single-minded proteins, suggesting additional roles for the encoded protein in the metabolism of xenobiotic compounds and the regulation of neurogenesis, respectively.

Gene ID: 9915

UniProt: Q9HBZ2

Pathways: Warburg Effect