Cofilin 2 antibody

Catalog No. ABIN7264069

Product Details anti-Cofilin 2 Antibody

Target: Cofilin 2 (CFL2)

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Cofilin 2 antibody is un-conjugated

Application: Western Blotting (WB), Immunofluorescence (IF)

Characteristics: Polyclonal Antibody

Purification: Affinity purification

Immunogen: Recombinant fusion protein of human CFL2 (NP_068733.1).

Isotype: IgG

Application Details

Application Notes: WB 1:500-1:2000 IF 1:50-1:100

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for Cofilin 2

Target: Cofilin 2 (CFL2)

Alternative Name: CFL2 (CFL2 Products)

Synonyms: NEM7 antibody, CFL2 antibody, zgc:77288 antibody, cf12 antibody, cofilin 2 antibody, cofilin 2 (non-muscle) antibody, cofilin 2 (muscle) antibody, cofilin 2, muscle antibody, cofilin-2 antibody, CFL2 antibody, cfl2 antibody, Cfl2 antibody, cf12 antibody, LOC100359205 antibody

Background: This gene encodes an intracellular protein that is involved in the regulation of actin-filament dynamics. This protein is a major component of intranuclear and cytoplasmic actin rods. It can bind G- and F-actin in a 1:1 ratio of cofilin to actin, and it reversibly controls actin polymerization and depolymerization in a pH -dependent manner. Mutations in this gene cause nemaline myopathy type 7, a form of congenital myopathy. Alternative splicing results in multiple transcript variants.

Molecular Weight:

Observed_MW: 18 kDa

Calculated_MW: 16 kDa/18 kDa

Gene ID: 1073

UniProt: Q9Y281

Pathways: Caspase Cascade in Apoptosis