IRS2 antibody
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- Target See all IRS2 Antibodies
- IRS2 (Insulin Receptor Substrate 2 (IRS2))
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Reactivity
- Human, Mouse, Rat
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Host
- Rabbit
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Clonality
- Polyclonal
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Conjugate
- This IRS2 antibody is un-conjugated
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Application
- Immunohistochemistry (IHC)
- Characteristics
- Polyclonal Antibody
- Purification
- Affinity purification
- Immunogen
- Recombinant fusion protein of human IRS2 (NP_003740.2).
- Isotype
- IgG
- Top Product
- Discover our top product IRS2 Primary Antibody
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- Application Notes
- IHC 1:50-1:100
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 1 mg/mL
- Buffer
- PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3
- Preservative
- Sodium azide
- Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Storage
- -20 °C
- Storage Comment
- Store at -20°C. Avoid freeze / thaw cycles.
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- Target
- IRS2 (Insulin Receptor Substrate 2 (IRS2))
- Alternative Name
- IRS2 (IRS2 Products)
- Synonyms
- IRS2 antibody, si:dkeyp-24d6.1 antibody, IRS-2 antibody, 4PS antibody, Irs-2 antibody, insulin receptor substrate 2 antibody, insulin receptor substrate 2a antibody, insulin receptor substrate 2b antibody, IRS2 antibody, irs2a antibody, irs2b antibody, Irs2 antibody
- Background
- This gene encodes the insulin receptor substrate 2, a cytoplasmic signaling molecule that mediates effects of insulin, insulin-like growth factor 1, and other cytokines by acting as a molecular adaptor between diverse receptor tyrosine kinases and downstream effectors. The product of this gene is phosphorylated by the insulin receptor tyrosine kinase upon receptor stimulation, as well as by an interleukin 4 receptor-associated kinase in response to IL4 treatment.
- Gene ID
- 8660
- UniProt
- Q9Y4H2
- Pathways
- Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway, Positive Regulation of Peptide Hormone Secretion, Response to Growth Hormone Stimulus, Carbohydrate Homeostasis, Regulation of Carbohydrate Metabolic Process
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