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FLT3 antibody

FLT3 Reactivity: Human, Mouse, Rat WB, IHC Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN7012052
  • Target See all FLT3 Antibodies
    FLT3 (Fms-Related tyrosine Kinase 3 (FLT3))
    Reactivity
    • 141
    • 53
    • 6
    • 5
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Human, Mouse, Rat
    Host
    • 143
    • 14
    • 2
    • 1
    Rabbit
    Clonality
    • 144
    • 16
    Polyclonal
    Conjugate
    • 67
    • 12
    • 10
    • 8
    • 7
    • 5
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    This FLT3 antibody is un-conjugated
    Application
    • 113
    • 69
    • 42
    • 42
    • 31
    • 21
    • 18
    • 12
    • 8
    • 8
    • 4
    • 3
    • 2
    • 1
    • 1
    Western Blotting (WB), Immunohistochemistry (IHC)
    Characteristics
    Polyclonal Antibody
    Purification
    Affinity purification
    Immunogen
    Recombinant protein of human FLT3
    Isotype
    IgG
    Top Product
    Discover our top product FLT3 Primary Antibody
  • Application Notes
    WB 1:500-1:2000 IHC 1:50-1:100
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    1 mg/mL
    Buffer
    PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Storage
    -20 °C
    Storage Comment
    Store at -20°C. Avoid freeze / thaw cycles.
  • Target
    FLT3 (Fms-Related tyrosine Kinase 3 (FLT3))
    Alternative Name
    FLT3 (FLT3 Products)
    Synonyms
    FLT3 antibody, B230315G04 antibody, CD135 antibody, Flk-2 antibody, Flk2 antibody, Flt-3 antibody, Ly72 antibody, wmfl antibody, FLK-2 antibody, FLK2 antibody, STK1 antibody, fms related tyrosine kinase 3 antibody, FMS-like tyrosine kinase 3 antibody, fms-related tyrosine kinase 3 antibody, FLT3 antibody, Flt3 antibody
    Background
    This gene encodes a class III receptor tyrosine kinase that regulates hematopoiesis. This receptor is activated by binding of the fms-related tyrosine kinase 3 ligand to the extracellular domain, which induces homodimer formation in the plasma membrane leading to autophosphorylation of the receptor. The activated receptor kinase subsequently phosphorylates and activates multiple cytoplasmic effector molecules in pathways involved in apoptosis, proliferation, and differentiation of hematopoietic cells in bone marrow. Mutations that result in the constitutive activation of this receptor result in acute myeloid leukemia and acute lymphoblastic leukemia.
    Molecular Weight

    Observed_MW: 113 kDa

    Calculated_MW: 108 kDa/112 kDa

    Gene ID
    2322
    UniProt
    P36888
    Pathways
    RTK Signaling
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