EYA3 antibody

Catalog No. ABIN7263927

Product Details anti-EYA3 Antibody

Target: EYA3 (Eyes Absent Homolog 3 (EYA3))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This EYA3 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Characteristics: Polyclonal Antibody

Purification: Affinity purification

Immunogen: Recombinant fusion protein of human EYA3 (NP_001981.2).

Isotype: IgG

Application Details

Application Notes: WB 1:500-1:2000 IHC 1:50-1:200

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for EYA3

Target: EYA3 (Eyes Absent Homolog 3 (EYA3))

Alternative Name: EYA3 (EYA3 Products)

Synonyms: zgc:152966 antibody, si:ch211-195b13.2 antibody, Xeya3 antibody, MGC85199 antibody, EYA3 antibody, AI844637 antibody, EYA transcriptional coactivator and phosphatase 3 antibody, EYA transcriptional coactivator and phosphatase 3 L homeolog antibody, eya3 antibody, eya3.L antibody, EYA3 antibody, Eya3 antibody

Background: This gene encodes a member of the eyes absent (EYA) family of proteins. The encoded protein may act as a transcriptional activator and have a role during development. It can act as a mediator of chemoresistance and cell survival in Ewing sarcoma cells, where this gene is up-regulated via a micro-RNA that binds to the 3' UTR of the transcript. A similar protein in mice acts as a transcriptional activator. Alternative splicing of this gene results in multiple transcript variants.

Molecular Weight:

Observed_MW: 63 kDa

Calculated_MW: 48 kDa/56 kDa/57 kDa/58 kDa/62 kDa

Gene ID: 2140

UniProt: Q99504

Pathways: Positive Regulation of Response to DNA Damage Stimulus