Gasdermin B antibody

Catalog No. ABIN7011812

Product Details anti-Gasdermin B Antibody

Target: Gasdermin B (GSDMB)

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Gasdermin B antibody is un-conjugated

Application: Western Blotting (WB)

Characteristics: Polyclonal Antibody

Purification: Affinity purification

Immunogen: Recombinant fusion protein of human GSDMB (NP_001159431.1).

Isotype: IgG

Application Details

Application Notes: WB 1:500-1:2000

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for Gasdermin B

Target: Gasdermin B (GSDMB)

Alternative Name: GSDMB (GSDMB Products)

Synonyms: GSDML antibody, PRO2521 antibody, gasdermin B antibody, GSDMB antibody

Background: This gene encodes a member of the gasdermin-domain containing protein family. Other gasdermin-family genes are implicated in the regulation of apoptosis in epithelial cells, and are linked to cancer. Alternative splicing and the use of alternative promoters results in multiple transcript variants. Additional variants have been described, but they are candidates for nonsense-mediated mRNA decay (NMD) and are unlikely to be protein-coding.

Molecular Weight:

Observed_MW: 47 kDa

Calculated_MW: 18 kDa/45 kDa/46 kDa/47 kDa

Gene ID: 55876

UniProt: Q8TAX9