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CHMP4B antibody

CHMP4B Reactivity: Human, Mouse, Rat IHC Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN7011771
  • Target See all CHMP4B Antibodies
    CHMP4B (Charged Multivesicular Body Protein 4B (CHMP4B))
    Reactivity
    • 44
    • 21
    • 13
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 1
    Human, Mouse, Rat
    Host
    • 43
    • 1
    Rabbit
    Clonality
    • 43
    • 1
    Polyclonal
    Conjugate
    • 13
    • 4
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This CHMP4B antibody is un-conjugated
    Application
    • 20
    • 19
    • 17
    • 13
    • 13
    • 12
    • 5
    • 3
    • 3
    • 3
    Immunohistochemistry (IHC)
    Characteristics
    Polyclonal Antibody
    Purification
    Affinity purification
    Immunogen
    Recombinant fusion protein of human CHMP4B (NP_789782.1).
    Isotype
    IgG
    Top Product
    Discover our top product CHMP4B Primary Antibody
  • Application Notes
    IHC 1:50-1:200
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    1 mg/mL
    Buffer
    PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Storage
    -20 °C
    Storage Comment
    Store at -20°C. Avoid freeze / thaw cycles.
  • Target
    CHMP4B (Charged Multivesicular Body Protein 4B (CHMP4B))
    Alternative Name
    CHMP4B (CHMP4B Products)
    Synonyms
    C20orf178 antibody, CHMP4A antibody, CTPP3 antibody, CTRCT31 antibody, SNF7 antibody, SNF7-2 antibody, Shax1 antibody, VPS32B antibody, Vps32-2 antibody, dJ553F4.4 antibody, 2010012F05Rik antibody, C76846 antibody, Snf7-2 antibody, RGD1309846 antibody, RGD1565889 antibody, CHMP4b antibody, chmp4b antibody, chmp4b.S antibody, CHMP4c antibody, c20orf178 antibody, wu:fc96b02 antibody, zgc:55566 antibody, charged multivesicular body protein 4B antibody, charged multivesicular body protein 4Ba antibody, charged multivesicular body protein 4B L homeolog antibody, charged multivesicular body protein 4Bb antibody, CHMP4B antibody, Chmp4b antibody, chmp4ba antibody, chmp4b.L antibody, chmp4bb antibody
    Background
    This gene encodes a member of the chromatin-modifying protein/charged multivesicular body protein (CHMP) protein family. The protein is part of the endosomal sorting complex required for transport (ESCRT) complex III (ESCRT-III), which functions in the sorting of endocytosed cell-surface receptors into multivesicular endosomes. The ESCRT machinery also functions in the final abscisson stage of cytokinesis and in the budding of enveloped viruses such as HIV-1. The three proteins of the CHMP4 subfamily interact with programmed cell death 6 interacting protein (PDCD6IP, also known as ALIX), which also functions in the ESCRT pathway. The CHMP4 proteins assemble into membrane-attached 5-nm filaments that form circular scaffolds and promote or stabilize outward budding. These polymers are proposed to help generate the luminal vesicles of multivesicular bodies. Mutations in this gene result in autosomal dominant posterior polar cataracts.
    Gene ID
    128866
    UniProt
    Q9H444
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