BTNL2 antibody

Catalog No. ABIN7263105

Product Details anti-BTNL2 Antibody

Target: BTNL2 (Butyrophilin-Like 2 (MHC Class II Associated) (BTNL2))

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This BTNL2 antibody is un-conjugated

Application: Western Blotting (WB)

Characteristics: Polyclonal Antibody

Purification: Affinity purification

Immunogen: Recombinant fusion protein of human BTNL2 (NP_062548.1).

Isotype: IgG

Application Details

Application Notes: WB 1:500-1:2000

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for BTNL2

Target: BTNL2 (Butyrophilin-Like 2 (MHC Class II Associated) (BTNL2))

Alternative Name: BTNL2 (BTNL2 Products)

Synonyms: BTL-II antibody, HSBLMHC1 antibody, SS2 antibody, Ng9 antibody, BTLN2 antibody, Btl2 antibody, Gm315 antibody, NG9 antibody, BTNL2 antibody, butyrophilin like 2 antibody, butyrophilin-like 2 antibody, butyrophilin-like 2 (MHC class II associated) antibody, butyrophilin-like protein 2 antibody, BTNL2 antibody, Btnl2 antibody, LOC100348151 antibody

Background: This gene encodes a major histocompatibility complex, class II associated, type I transmembrane protein which belongs to the butyrophilin-like B7 family of immunoregulators. It is thought to be involved in immune surveillance, serving as a negative T-cell regulator by decreasing T-cell proliferation and cytokine release. The encoded protein contains an N-terminal signal peptide, two pairs of immunoglobulin-like domains, separated by a heptad peptide sequence, and a C-terminal transmembrane domain. Naturally occurring mutations in this gene are associated with sarcoidosis, rheumatoid arthritis, ulcerative colitis, inflammatory bowel disease, myositis, type 1 diabetes, systemic lupus erythematosus, acute coronary syndrome, and prostate cancer.

Molecular Weight:

Observed_MW: 60 kDa

Calculated_MW: 19 kDa/27 kDa/28 kDa/30 kDa/43 kDa/50 kDa

Gene ID: 56244

UniProt: Q9UIR0