90K antibody, BTBD17B antibody, MAC-2-BP antibody, TANGO10B antibody, Ppicap antibody, CyCAP antibody, MAC-2BP antibody, Tango10b antibody, lgals3bp antibody, zgc:136780 antibody, MAC2BP antibody, Mac-2 BP antibody, zgc:77059 antibody, galectin 3 binding protein antibody, lectin, galactoside-binding, soluble, 3 binding protein antibody, calcium activated nucleotidase 1 antibody, lectin, galactoside-binding, soluble, 3 binding protein a antibody, lectin, galactoside-binding, soluble, 3 binding protein b antibody, LGALS3BP antibody, Lgals3bp antibody, CANT1 antibody, lgals3bpa antibody, lgals3bpb antibody
Background
The galectins are a family of beta-galactoside-binding proteins implicated in modulating cell-cell and cell-matrix interactions. LGALS3BP has been found elevated in the serum of patients with cancer and in those infected by the human immunodeficiency virus (HIV). It appears to be implicated in immune response associated with natural killer (NK) and lymphokine-activated killer (LAK) cell cytotoxicity. Using fluorescence in situ hybridization the full length 90K cDNA has been localized to chromosome 17q25. The native protein binds specifically to a human macrophage-associated lectin known as Mac-2 and also binds galectin 1.