DR1 antibody

Catalog No. ABIN7011423

Product Details anti-DR1 Antibody

Target: DR1 (TATA-Binding Protein-Associated Phosphoprotein (DR1))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This DR1 antibody is un-conjugated

Application: Immunohistochemistry (IHC), Immunofluorescence (IF)

Characteristics: Polyclonal Antibody

Purification: Affinity purification

Immunogen: Recombinant fusion protein of human DR1 (NP_001929.1).

Isotype: IgG

Application Details

Application Notes: IHC 1:50-1:200 IF 1:50-1:200

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for DR1

Target: DR1 (TATA-Binding Protein-Associated Phosphoprotein (DR1))

Alternative Name: DR1 (DR1 Products)

Synonyms: BG:DS00929.3 antibody, CG4185 antibody, Dmel\\CG4185 antibody, Dr1 antibody, NC2 beta antibody, Nc2b antibody, dDr1 antibody, dNC2 antibody, wu:fj15f04 antibody, zgc:152914 antibody, 1700121L09Rik antibody, Dr1l antibody, NC2 antibody, NC2beta antibody, NC2-BETA antibody, Negative Cofactor 2beta antibody, TATA-BINDING PROTEIN-ASSOCIATED PHOSPHOPROTEIN antibody, TATA-binding protein-associated phosphoprotein antibody, putative tata-binding protein-associated phosphoprotein antibody, down-regulator of transcription 1 antibody, down-regulator of transcription 1, TBP-binding (negative cofactor 2) antibody, NC2beta antibody, ECU11_0730 antibody, EDI_229030 antibody, PTRG_08168 antibody, Smp_160150 antibody, EBI_26279 antibody, EBI_23074 antibody, VDBG_02216 antibody, dr1 antibody, Dr1 antibody, DR1 antibody

Background: This gene encodes a TBP- (TATA box-binding protein) associated phosphoprotein that represses both basal and activated levels of transcription. The encoded protein is phosphorylated in vivo and this phosphorylation affects its interaction with TBP. This protein contains a histone fold motif at the amino terminus, a TBP-binding domain, and a glutamine- and alanine-rich region. The binding of DR1 repressor complexes to TBP-promoter complexes may establish a mechanism in which an altered DNA conformation, together with the formation of higher order complexes, inhibits the assembly of the preinitiation complex and controls the rate of RNA polymerase II transcription.

Gene ID: 1810

UniProt: Q01658