ATOX1 antibody

Catalog No. ABIN7262771

Product Details anti-ATOX1 Antibody

Target: ATOX1 (ATX1 Antioxidant Protein 1 Homolog (ATOX1))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This ATOX1 antibody is un-conjugated

Application: Immunofluorescence (IF)

Characteristics: Polyclonal Antibody

Purification: Affinity purification

Immunogen: Recombinant fusion protein of human ATOX1 (NP_004036.1).

Isotype: IgG

Application Details

Application Notes: IF 1:50-1:100

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for ATOX1

Target: ATOX1 (ATX1 Antioxidant Protein 1 Homolog (ATOX1))

Alternative Name: ATOX1 (ATOX1 Products)

Synonyms: ATX1 antibody, HAH1 antibody, AI256639 antibody, Atx1 antibody, CG12562 antibody, CG32446 antibody, DmAtox1 antibody, Dmel\\CG32446 antibody, atx1 antibody, hah1 antibody, DDBDRAFT_0185901 antibody, DDBDRAFT_0266724 antibody, DDB_0185901 antibody, DDB_0266724 antibody, SAH antibody, ATOX1 antibody, antioxidant 1 copper chaperone antibody, Antioxidant 1 copper chaperone antibody, copper transport protein antibody, ATX1 antioxidant protein 1 homolog antibody, ATOX1 antibody, Atox1 antibody, atox1 antibody

Background: This gene encodes a copper chaperone that plays a role in copper homeostasis by binding and transporting cytosolic copper to ATPase proteins in the trans-Golgi network for later incorporation to the ceruloplasmin. This protein also functions as an antioxidant against superoxide and hydrogen peroxide, and therefore, may play a significant role in cancer carcinogenesis. Because of its cytogenetic location, this gene represents a candidate gene for 5q-syndrome.

Gene ID: 475

UniProt: O00244

Pathways: Transition Metal Ion Homeostasis