TRAF3IP2 antibody

Catalog No. ABIN7262707

Product Details anti-TRAF3IP2 Antibody

Target: TRAF3IP2 (TRAF3 Interacting Protein 2 (TRAF3IP2))

Reactivity: Human, Rat, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This TRAF3IP2 antibody is un-conjugated

Application: Immunohistochemistry (IHC)

Characteristics: Polyclonal Antibody

Purification: Affinity purification

Immunogen: Recombinant fusion protein of human TRAF3IP2 (NP_679211.2).

Isotype: IgG

Application Details

Application Notes: IHC 1:50-1:200

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for TRAF3IP2

Target: TRAF3IP2 (TRAF3 Interacting Protein 2 (TRAF3IP2))

Alternative Name: TRAF3IP2 (TRAF3IP2 Products)

Synonyms: ACT1 antibody, C6orf2 antibody, C6orf4 antibody, C6orf5 antibody, C6orf6 antibody, CIKS antibody, PSORS13 antibody, AI429613 antibody, Act1 antibody, RGD1304768 antibody, C6ORF4 antibody, t3jam antibody, traf3ip2 antibody, TRAF3IP2 antibody, MGC134034 antibody, TRAF3 interacting protein 2 antibody, Traf3 interacting protein 2 antibody, adapter protein CIKS antibody, TRAF3 interacting protein 2 L homeolog antibody, TRAF3IP2 antibody, Traf3ip2 antibody, LOC100473939 antibody, traf3ip3.L antibody, traf3ip3 antibody

Background: This gene encodes a protein involved in regulating responses to cytokines by members of the Rel/NF-kappaB transcription factor family. These factors play a central role in innate immunity in response to pathogens, inflammatory signals and stress. This gene product interacts with TRAF proteins (tumor necrosis factor receptor-associated factors) and either I-kappaB kinase or MAP kinase to activate either NF-kappaB or Jun kinase. Several alternative transcripts encoding different isoforms have been identified. Another transcript, which does not encode a protein and is transcribed in the opposite orientation, has been identified. Overexpression of this transcript has been shown to reduce expression of at least one of the protein encoding transcripts, suggesting it has a regulatory role in the expression of this gene.

Gene ID: 10758

UniProt: O43734

Pathways: Production of Molecular Mediator of Immune Response