SETMAR antibody

Catalog No. ABIN7262651

Product Details anti-SETMAR Antibody

Target: SETMAR (SET Domain and Mariner Transposase Fusion Gene (SETMAR))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This SETMAR antibody is un-conjugated

Application: Immunofluorescence (IF)

Characteristics: Polyclonal Antibody

Purification: Affinity purification

Immunogen: Recombinant fusion protein of human SETMAR (NP_006506.3).

Isotype: IgG

Application Details

Application Notes: IF 1:20-1:50

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for SETMAR

Target: SETMAR (SET Domain and Mariner Transposase Fusion Gene (SETMAR))

Alternative Name: SETMAR (SETMAR Products)

Synonyms: HsMar1 antibody, METNASE antibody, Mar1 antibody, 5830404F24Rik antibody, Etet2 antibody, SETMAR antibody, zgc:172212 antibody, SET domain and mariner transposase fusion gene antibody, SET domain without mariner transposase fusion antibody, histone-lysine N-methyltransferase SETMAR antibody, SETMAR antibody, Setmar antibody, LOC470738 antibody, setmar antibody, LOC703880 antibody, LOC100447656 antibody, LOC100586616 antibody

Background: This gene encodes a fusion protein that contains an N-terminal histone-lysine N-methyltransferase domain and a C-terminal mariner transposase domain. The encoded protein binds DNA and functions in DNA repair activities including non-homologous end joining and double strand break repair. The SET domain portion of this protein specifically methylates histone H3 lysines 4 and 36. This gene exists as a fusion gene only in anthropoid primates, other organisms lack mariner transposase domain. Alternate splicing results in multiple transcript variants.

Gene ID: 6419

UniProt: Q53H47

Pathways: Positive Regulation of Response to DNA Damage Stimulus