PDCD6 antibody

Catalog No. ABIN7262575

Product Details anti-PDCD6 Antibody

Target: PDCD6 (Programmed Cell Death 6 (PDCD6))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This PDCD6 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF)

Characteristics: Polyclonal Antibody

Purification: Affinity purification

Immunogen: Recombinant fusion protein of human PDCD6 (NP_037364.1).

Isotype: IgG

Application Details

Application Notes: WB 1:500-1:2000 IHC 1:50-1:200 IF 1:50-1:100

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for PDCD6

Target: PDCD6 (Programmed Cell Death 6 (PDCD6))

Alternative Name: PDCD6 (PDCD6 Products)

Synonyms: pdcd6 antibody, MGC52821 antibody, MGC132114 antibody, zgc:63952 antibody, PDCD6 antibody, ALG-2 antibody, PEF1B antibody, AV299538 antibody, Alg2 antibody, MA-3 antibody, PS2 antibody, alg-2 antibody, programmed cell death 6 L homeolog antibody, programmed cell death 6 antibody, pdcd6.L antibody, pdcd6 antibody, PDCD6 antibody, Pdcd6 antibody

Background: This gene encodes a calcium-binding protein belonging to the penta-EF-hand protein family. Calcium binding is important for homodimerization and for conformational changes required for binding to other protein partners. This gene product participates in T cell receptor-, Fas-, and glucocorticoid-induced programmed cell death. In mice deficient for this gene product, however, apoptosis was not blocked suggesting this gene product is functionally redundant. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene, and a pseudogene of this gene is also located on the short arm of chromosome 5.

Molecular Weight:

Observed_MW: 16 kDa

Calculated_MW: 7 kDa/21 kDa

Gene ID: 10016

UniProt: O75340

Pathways: Positive Regulation of Endopeptidase Activity