Melanophilin antibody
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- Target See all Melanophilin (MLPH) Antibodies
- Melanophilin (MLPH)
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Reactivity
- Human, Mouse, Rat
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Host
- Rabbit
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Clonality
- Polyclonal
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Conjugate
- This Melanophilin antibody is un-conjugated
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Application
- Western Blotting (WB), Immunofluorescence (IF)
- Characteristics
- Polyclonal Antibody
- Purification
- Affinity purification
- Immunogen
- Recombinant fusion protein of human MLPH (NP_077006.1).
- Isotype
- IgG
- Top Product
- Discover our top product MLPH Primary Antibody
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- Application Notes
- WB 1:500-1:2000 IF 1:50-1:200
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 1 mg/mL
- Buffer
- PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3
- Preservative
- Sodium azide
- Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Storage
- -20 °C
- Storage Comment
- Store at -20°C. Avoid freeze / thaw cycles.
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- Target
- Melanophilin (MLPH)
- Alternative Name
- MLPH (MLPH Products)
- Synonyms
- MGC155106 antibody, LOC100222096 antibody, 2210418F23Rik antibody, 5031433I09Rik antibody, AW228792 antibody, D1Wsu84e antibody, Slac-2a antibody, l(1)-3Rk antibody, l1Rk3 antibody, ln antibody, SLAC2-A antibody, melanophilin antibody, MLPH antibody, mlph antibody, Mlph antibody
- Background
- This gene encodes a member of the exophilin subfamily of Rab effector proteins. The protein forms a ternary complex with the small Ras-related GTPase Rab27A in its GTP-bound form and the motor protein myosin Va. A similar protein complex in mouse functions to tether pigment-producing organelles called melanosomes to the actin cytoskeleton in melanocytes, and is required for visible pigmentation in the hair and skin. A mutation in this gene results in Griscelli syndrome type 3, which is characterized by a silver-gray hair color and abnormal pigment distribution in the hair shaft. Several alternatively spliced transcript variants encoding different isoforms have been found for this gene.
- Molecular Weight
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Observed_MW: 75 kDa
Calculated_MW: 50 kDa/52 kDa/60 kDa/62 kDa/65 kDa
- Gene ID
- 79083
- UniProt
- Q9BV36
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