MAPRE2 antibody, DKFZp459O163 antibody, EB1 antibody, EB2 antibody, RP1 antibody, AI314113 antibody, C820009F03Rik antibody, D18Abb1e antibody, mapre2-A antibody, microtubule associated protein RP/EB family member 2 antibody, microtubule-associated protein, RP/EB family, member 2 antibody, microtubule associated protein RP/EB family member 2 S homeolog antibody, MAPRE2 antibody, Mapre2 antibody, mapre2.S antibody
Background
The protein encoded by this gene shares significant homology to the adenomatous polyposis coli (APC) protein-binding EB1 gene family. This protein is a microtubule-associated protein that is necessary for spindle symmetry during mitosis. It is thought to play a role in the tumorigenesis of colorectal cancers and the proliferative control of normal cells. Alternative splicing of this gene results in multiple transcript variants.