GRK1 antibody

Catalog No. ABIN7262347

Product Details anti-GRK1 Antibody

Target: GRK1 (G Protein-Coupled Receptor Kinase 1 (GRK1))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This GRK1 antibody is un-conjugated

Application: Western Blotting (WB), Immunofluorescence (IF)

Characteristics: Polyclonal Antibody

Purification: Affinity purification

Immunogen: Recombinant fusion protein of human GRK1 (NP_002920.1).

Isotype: IgG

Application Details

Application Notes: WB 1:200-1:2000 IF 1:50-1:200

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for GRK1

Target: GRK1 (G Protein-Coupled Receptor Kinase 1 (GRK1))

Alternative Name: GRK1 (GRK1 Products)

Synonyms: GPRK1 antibody, RHOK antibody, RK antibody, Gprk1 antibody, Rhok antibody, Rk antibody, CG40129 antibody, CT4320 antibody, Dmel\\CG40129 antibody, Gprk-1 antibody, Rok antibody, gprk1 antibody, grk1 antibody, zgc:112194 antibody, G protein-coupled receptor kinase 1 antibody, G protein-coupled receptor kinase 1 a antibody, G protein-coupled receptor kinase 1 b antibody, GRK1 antibody, Grk1 antibody, Gprk1 antibody, grk1a antibody, grk1b antibody

Background: This gene encodes a member of the guanine nucleotide-binding protein (G protein)-coupled receptor kinase subfamily of the Ser/Thr protein kinase family. The protein phosphorylates rhodopsin and initiates its deactivation. Defects in GRK1 are known to cause Oguchi disease 2 (also known as stationary night blindness Oguchi type-2).

Molecular Weight:

Observed_MW: 65 kDa

Calculated_MW: 63 kDa

Gene ID: 6011

UniProt: Q15835

Pathways: Regulation of G-Protein Coupled Receptor Protein Signaling, Phototransduction