zgc:92200 antibody, wu:fa04c03 antibody, wu:fj80b06 antibody, wu:fj80h04 antibody, ACAS2 antibody, ACECS antibody, ACS antibody, ACSA antibody, dJ1161H23.1 antibody, 1110017C11Rik antibody, ACAS antibody, Acas1 antibody, Acas2 antibody, AceCS1 antibody, Acs1 antibody, acyl-CoA synthetase short chain family member 2 antibody, acetyl-coenzyme A synthetase, cytoplasmic antibody, acyl-CoA synthetase short-chain family member 2 antibody, acyl-CoA synthetase short chain family member 1 antibody, ACSS2 antibody, LOC100179555 antibody, LOC100211402 antibody, acss2 antibody, ACSS1 antibody, Acss2 antibody
Background
This gene encodes a cytosolic enzyme that catalyzes the activation of acetate for use in lipid synthesis and energy generation. The protein acts as a monomer and produces acetyl-CoA from acetate in a reaction that requires ATP. Expression of this gene is regulated by sterol regulatory element-binding proteins, transcription factors that activate genes required for the synthesis of cholesterol and unsaturated fatty acids. Alternative splicing results in multiple transcript variants.