Fibromodulin antibody
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- Target See all Fibromodulin (FMOD) Antibodies
- Fibromodulin (FMOD)
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Reactivity
- Human, Rat, Mouse
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Host
- Rabbit
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Clonality
- Polyclonal
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Conjugate
- This Fibromodulin antibody is un-conjugated
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Application
- Western Blotting (WB), Immunohistochemistry (IHC)
- Characteristics
- Polyclonal Antibody
- Purification
- Affinity purification
- Immunogen
- Recombinant fusion protein of human FMOD (NP_002014.2).
- Isotype
- IgG
- Top Product
- Discover our top product FMOD Primary Antibody
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- Application Notes
- WB 1:500-1:2000 IHC 1:50-1:200
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 1 mg/mL
- Buffer
- PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3
- Preservative
- Sodium azide
- Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Storage
- -20 °C
- Storage Comment
- Store at -20°C. Avoid freeze / thaw cycles.
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- Target
- Fibromodulin (FMOD)
- Alternative Name
- FMOD (FMOD Products)
- Synonyms
- FMOD antibody, AI131919 antibody, AU041740 antibody, SLRR2E antibody, LOC100286414 antibody, sc:d0415 antibody, si:dkey-31j12.4 antibody, LOC100229381 antibody, FM antibody, fibromodulin antibody, fibromodulin b antibody, FMOD antibody, Fmod antibody, LOC100286414 antibody, fmodb antibody
- Background
- Fibromodulin belongs to the family of small interstitial proteoglycans. The encoded protein possesses a central region containing leucine-rich repeats with 4 keratan sulfate chains, flanked by terminal domains containing disulphide bonds. Owing to the interaction with type I and type II collagen fibrils and in vitro inhibition of fibrillogenesis, the encoded protein may play a role in the assembly of extracellular matrix. It may also regulate TGF-beta activities by sequestering TGF-beta into the extracellular matrix. Sequence variations in this gene may be associated with the pathogenesis of high myopia. Alternative splicing results in multiple transcript variants.
- Molecular Weight
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Observed_MW: 45 kDa
Calculated_MW: 43 kDa
- Gene ID
- 2331
- UniProt
- Q06828
- Pathways
- Glycosaminoglycan Metabolic Process
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