Adenylosuccinate Lyase antibody
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- Target See all Adenylosuccinate Lyase (ADSL) Antibodies
- Adenylosuccinate Lyase (ADSL)
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Reactivity
- Human, Mouse, Rat
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Host
- Rabbit
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Clonality
- Polyclonal
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Conjugate
- This Adenylosuccinate Lyase antibody is un-conjugated
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Application
- Western Blotting (WB), Immunofluorescence (IF)
- Characteristics
- Polyclonal Antibody
- Purification
- Affinity purification
- Immunogen
- Recombinant fusion protein of human ADSL (NP_000017.1).
- Isotype
- IgG
- Top Product
- Discover our top product ADSL Primary Antibody
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- Application Notes
- WB 1:500-1:2000 IF 1:20-1:100
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 1 mg/mL
- Buffer
- PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3
- Preservative
- Sodium azide
- Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Storage
- -20 °C
- Storage Comment
- Store at -20°C. Avoid freeze / thaw cycles.
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- Target
- Adenylosuccinate Lyase (ADSL)
- Alternative Name
- ADSL (ADSL Products)
- Background
- The protein encoded by this gene belongs to the lyase 1 family. It is an essential enzyme involved in purine metabolism, and catalyzes two non-sequential reactions in the de novo purine biosynthetic pathway: the conversion of succinylaminoimidazole carboxamide ribotide (SAICAR) to aminoimidazole carboxamide ribotide (AICAR) and the conversion of adenylosuccinate (S-AMP) to adenosine monophosphate (AMP). Mutations in this gene are associated with adenylosuccinase deficiency (ADSLD), a disorder marked with psychomotor retardation, epilepsy or autistic features. Alternatively spliced transcript variants have been found for this gene.
- Molecular Weight
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Observed_MW: 55 kDa
Calculated_MW: 48 kDa/54 kDa
- Gene ID
- 158
- UniProt
- P30566
- Pathways
- Ribonucleoside Biosynthetic Process
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