C8orf4 antibody
C8orf4
Reactivity: Human, Mouse, Rat
IHC
Host: Rabbit
Polyclonal
unconjugated
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- Target See all C8orf4 Antibodies
- C8orf4 (Chromosome 8 Open Reading Frame 4 (C8orf4))
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Reactivity
- Human, Mouse, Rat
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Host
- Rabbit
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Clonality
- Polyclonal
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Conjugate
- This C8orf4 antibody is un-conjugated
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Application
- Immunohistochemistry (IHC)
- Characteristics
- Polyclonal Antibody
- Purification
- Affinity purification
- Immunogen
- Recombinant fusion protein of human C8orf4 (NP_064515.1).
- Isotype
- IgG
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anti-Chromosome 8 Open Reading Frame 4 (C8orf4) antibody
C8orf4 Reactivity: Human, Mouse IHC, ELISA Host: Rabbit Polyclonal unconjugated
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- Application Notes
- IHC 1:50-1:200
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 1 mg/mL
- Buffer
- PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3
- Preservative
- Sodium azide
- Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Storage
- -20 °C
- Storage Comment
- Store at -20°C. Avoid freeze / thaw cycles.
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- Target
- C8orf4 (Chromosome 8 Open Reading Frame 4 (C8orf4))
- Alternative Name
- C8orf4 (C8orf4 Products)
- Background
- This gene encodes a small, monomeric, predominantly unstructured protein that functions as a positive regulator of the Wnt/beta-catenin signaling pathway. This protein interacts with a repressor of beta-catenin mediated transcription at nuclear speckles. It is thought to competitively block interactions of the repressor with beta-catenin, resulting in up-regulation of beta-catenin target genes. The encoded protein may also play a role in the NF-kappaB and ERK1/2 signaling pathways. Expression of this gene may play a role in the proliferation of several types of cancer including thyroid cancer, breast cancer and hematological malignancies.
- Gene ID
- 56892
- UniProt
- Q9NR00
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