TADA3L antibody
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- Target See all TADA3L (TADA3) Antibodies
- TADA3L (TADA3) (Transcriptional Adaptor 3 (TADA3))
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Reactivity
- Human, Mouse, Rat
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Host
- Rabbit
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Clonality
- Polyclonal
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Conjugate
- This TADA3L antibody is un-conjugated
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Application
- Immunofluorescence (IF)
- Characteristics
- Polyclonal Antibody
- Purification
- Affinity purification
- Immunogen
- Recombinant fusion protein of human TADA3 (NP_597814.1).
- Isotype
- IgG
- Top Product
- Discover our top product TADA3 Primary Antibody
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- Application Notes
- IF 1:50-1:200
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 1 mg/mL
- Buffer
- PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3
- Preservative
- Sodium azide
- Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Storage
- -20 °C
- Storage Comment
- Store at -20°C. Avoid freeze / thaw cycles.
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- Target
- TADA3L (TADA3) (Transcriptional Adaptor 3 (TADA3))
- Alternative Name
- TADA3 (TADA3 Products)
- Synonyms
- ADA3 antibody, NGG1 antibody, STAF54 antibody, TADA3L antibody, hADA3 antibody, Tada3l antibody, 1110004B19Rik antibody, AI987856 antibody, fa03f04 antibody, tada3 antibody, wu:fa03f04 antibody, zgc:63596 antibody, ada3 antibody, ada3-A antibody, ngg1 antibody, tada3l antibody, tada3l-a antibody, ada3-B antibody, tada3l-B antibody, transcriptional adaptor 3 antibody, transcriptional adapter 3 pseudogene antibody, transcriptional adaptor 3 (NGG1 homolog, yeast)-like antibody, transcriptional adaptor 3 L homeolog antibody, transcriptional adaptor 3 S homeolog antibody, TADA3 antibody, Tada3 antibody, LOC732883 antibody, LOC100061462 antibody, tada3 antibody, LOC100619707 antibody, tada3l antibody, tada3.L antibody, tada3.S antibody
- Background
- DNA-binding transcriptional activator proteins increase the rate of transcription by interacting with the transcriptional machinery bound to the basal promoter in conjunction with adaptor proteins, possibly by acetylation and destabilization of nucleosomes. The protein encoded by this gene is a transcriptional activator adaptor and a component of the histone acetyl transferase (HAT) coactivator complex which plays a crucial role in chromatin modulation and cell cycle progression. Along with the other components of the complex, this protein links transcriptional activators bound to specific promoters, to histone acetylation and the transcriptional machinery. The protein is also involved in the stabilization and activation of the p53 tumor suppressor protein that plays a role in the cellular response to DNA damage. Alternate splicing results in multiple transcript variants of this gene.
- Gene ID
- 10474
- UniProt
- O75528
- Pathways
- Intracellular Steroid Hormone Receptor Signaling Pathway
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