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ATP7B antibody
ATP7B
Reactivity: Human, Mouse
IF
Host: Rabbit
Polyclonal
unconjugated
Product Details anti-ATP7B Antibody
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Target
See all ATP7B Antibodies
ATP7B
(ATPase, Cu++ Transporting, beta Polypeptide (ATP7B))
Reactivity
All reactivities for ATP7B antibodies
Human, Mouse
Host
All hosts for ATP7B antibodies
Rabbit
Clonality
All clonalities for ATP7B antibodies
Polyclonal
Conjugate
All conjugates for ATP7B antibodies
This ATP7B antibody is un-conjugated
Application
All applications for ATP7B antibodies
Immunofluorescence (IF)
Characteristics
Polyclonal Antibody
Purification
Affinity purification
Immunogen
Recombinant fusion protein of human ATP7B (NP_001230111.1).
Isotype
IgG
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Discover our top product ATP7B Primary Antibody
Alternatives
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Application Details
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Application Notes
IF 1:50-1:200
Restrictions
For Research Use only
Handling
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Format
Liquid
Concentration
1 mg/mL
Buffer
PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3
Preservative
Sodium azide
Precaution of Use
This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage
-20 °C
Storage Comment
Store at -20°C. Avoid freeze / thaw cycles.
Target Details for ATP7B
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Target
ATP7B
(ATPase, Cu++ Transporting, beta Polypeptide (ATP7B))
Alternative Name
ATP7B (ATP7B Products )
Synonyms
PWD antibody, WC1 antibody, WD antibody, WND antibody, Atp7a antibody, tx antibody, Hts antibody, PINA antibody, Wd antibody, ATP7B antibody, ATPase copper transporting beta antibody, ATPase, Cu++ transporting, beta polypeptide antibody, ATPase, Cu++ transporting, beta polypeptide (Wilson disease) antibody, copper-transporting ATPase 2 antibody, ATP7B antibody, Atp7b antibody, atp7b antibody, LOC592143 antibody
Background
This gene is a member of the P-type cation transport ATPase family and encodes a protein with several membrane-spanning domains, an ATPase consensus sequence, a hinge domain, a phosphorylation site, and at least 2 putative copper-binding sites. This protein functions as a monomer, exporting copper out of the cells, such as the efflux of hepatic copper into the bile. Alternate transcriptional splice variants, encoding different isoforms with distinct cellular localizations, have been characterized. Mutations in this gene have been associated with Wilson disease (WD).
Gene ID
540
UniProt
P35670
Pathways
Transition Metal Ion Homeostasis , Ribonucleoside Biosynthetic Process
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