Serotonin Receptor 2B antibody

Catalog No. ABIN7261616

Product Details anti-Serotonin Receptor 2B Antibody

Target: Serotonin Receptor 2B (HTR2B)

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Serotonin Receptor 2B antibody is un-conjugated

Application: Immunohistochemistry (IHC), Immunofluorescence (IF)

Characteristics: Polyclonal Antibody

Purification: Affinity purification

Immunogen: Recombinant fusion protein of human HTR2B (NP_000858.3).

Isotype: IgG

Application Details

Application Notes: IHC 1:50-1:200 IF 1:10-1:100

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for Serotonin Receptor 2B

Target: Serotonin Receptor 2B (HTR2B)

Alternative Name: HTR2B (HTR2B Products)

Synonyms: 5-HT2B antibody, 5HT2B antibody, 5htr2b antibody, HTR2B antibody, 5ht2b antibody, zgc:194094 antibody, zgc:194119 antibody, AJ012488 antibody, AV377389 antibody, 5-HT(2B) antibody, 5-hydroxytryptamine receptor 2B antibody, 5-hydroxytryptamine (serotonin) receptor 2B, G protein-coupled antibody, 5-hydroxytryptamine (serotonin) receptor 2B antibody, HTR2B antibody, htr2b antibody, Htr2b antibody

Background: This gene encodes one of the several different receptors for 5-hydroxytryptamine (serotonin) that belongs to the G-protein coupled receptor 1 family. Serotonin is a biogenic hormone that functions as a neurotransmitter, a hormone, and a mitogen. Serotonin receptors mediate many of the central and peripheral physiologic functions of serotonin, including regulation of cardiovascular functions and impulsive behavior. Population and family-based analyses of a minor allele (glutamine-to-stop substitution, designated Q20*) which blocks expression of this protein, and knockout studies in mice, suggest a role for this gene in impulsivity. However, other factors, such as elevated testosterone levels, may also be involved. Alternatively spliced transcript variants have been found for this gene.

Gene ID: 3357

UniProt: P41595

Pathways: JAK-STAT Signaling, Inositol Metabolic Process, Regulation of G-Protein Coupled Receptor Protein Signaling, Regulation of Carbohydrate Metabolic Process