fb43c01 antibody, wu:fb43c01 antibody, zgc:55788 antibody, rab6 antibody, MGC53077 antibody, rab6b antibody, rab6a' antibody, MGC76176 antibody, LOC692966 antibody, RAB6 antibody, 2610028L11Rik antibody, AA419671 antibody, Rab6 antibody, RCO4-3 antibody, Rab6b antibody, RAB6A, member RAS oncogene family antibody, RAB6A, member RAS oncogene family S homeolog antibody, ras small monomeric GTPase Rab6 antibody, ras-related protein Rab-6A antibody, rab6a antibody, rab6a.S antibody, LOC692966 antibody, RAB6A antibody, Rab6a antibody
Background
This gene encodes a member of the RAB family, which belongs to the small GTPase superfamily. GTPases of the RAB family bind to various effectors to regulate the targeting and fusion of transport carriers to acceptor compartments. This protein is located at the Golgi apparatus, which regulates trafficking in both a retrograde (from early endosomes and Golgi to the endoplasmic reticulum) and an anterograde (from the Golgi to the plasma membrane) directions. Myosin II is an effector of this protein in these processes. This protein is also involved in assembly of human cytomegalovirus (HCMV) by interacting with the cellular protein Bicaudal D1, which interacts with the HCMV virion tegument protein, pp150. Multiple alternatively spliced transcript variants encoding different isoforms have been identified.