HAX1 antibody
-
- Target See all HAX1 Antibodies
- HAX1 (HCLS1 Associated Protein X-1 (HAX1))
-
Reactivity
- Human, Mouse, Rat
-
Host
- Rabbit
-
Clonality
- Polyclonal
-
Conjugate
- This HAX1 antibody is un-conjugated
-
Application
- Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF)
- Characteristics
- Polyclonal Antibody
- Purification
- Affinity purification
- Immunogen
- Recombinant fusion protein of human HAX1 (NP_006109.2).
- Isotype
- IgG
- Top Product
- Discover our top product HAX1 Primary Antibody
-
-
- Application Notes
- WB 1:500-1:2000 IHC 1:50-1:200 IF 1:10-1:100
- Restrictions
- For Research Use only
-
- Format
- Liquid
- Concentration
- 1 mg/mL
- Buffer
- PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3
- Preservative
- Sodium azide
- Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Storage
- -20 °C
- Storage Comment
- Store at -20°C. Avoid freeze / thaw cycles.
-
- Target
- HAX1 (HCLS1 Associated Protein X-1 (HAX1))
- Alternative Name
- HAX1 (HAX1 Products)
- Synonyms
- HAX1 antibody, hax1 antibody, HCLSBP1 antibody, HS1BP1 antibody, SCN3 antibody, HAX-1 antibody, Hs1bp1 antibody, HSP1BP-1 antibody, SIG-111 antibody, Silg111 antibody, mHAX-1s antibody, HCLS1 associated protein X-1 antibody, HCLS1 associated X-1 antibody, HAX1 antibody, hax1 antibody, Hax1 antibody
- Background
- The protein encoded by this gene is known to associate with hematopoietic cell-specific Lyn substrate 1, a substrate of Src family tyrosine kinases. It also interacts with the product of the polycystic kidney disease 2 gene, mutations in which are associated with autosomal-dominant polycystic kidney disease, and with the F-actin-binding protein, cortactin. It was earlier thought that this gene product is mainly localized in the mitochondria, however, recent studies indicate it to be localized in the cell body. Mutations in this gene result in autosomal recessive severe congenital neutropenia, also known as Kostmann disease. Two transcript variants encoding different isoforms have been found for this gene.
- Molecular Weight
-
Observed_MW: 36 kDa
Calculated_MW: 14 kDa/21 kDa/26 kDa/28 kDa/31 kDa/32 kDa
- Gene ID
- 10456
- UniProt
- O00165
- Pathways
- Regulation of Actin Filament Polymerization
-