LITAF antibody
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- Target See all LITAF Antibodies
- LITAF (Lipopolysaccharide-Induced Tumor Necrosis Factor-alpha Factor (LITAF))
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Reactivity
- Human, Mouse
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Host
- Rabbit
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Clonality
- Polyclonal
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Conjugate
- This LITAF antibody is un-conjugated
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Application
- Western Blotting (WB), Immunohistochemistry (IHC)
- Specificity
- This antibody ist KO validated.
- Characteristics
- Polyclonal Antibody
- Purification
- Affinity purification
- Grade
- KO Validated
- Immunogen
- Recombinant fusion protein of human LITAF (NP_004853.2).
- Isotype
- IgG
- Top Product
- Discover our top product LITAF Primary Antibody
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- Application Notes
- WB 1:500-1:2000 IHC 1:50-1:200
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 1 mg/mL
- Buffer
- PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3
- Preservative
- Sodium azide
- Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Storage
- -20 °C
- Storage Comment
- Store at -20°C. Avoid freeze / thaw cycles.
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- Target
- LITAF (Lipopolysaccharide-Induced Tumor Necrosis Factor-alpha Factor (LITAF))
- Alternative Name
- LITAF (LITAF Products)
- Synonyms
- PIG7 antibody, SIMPLE antibody, TP53I7 antibody, EET-1 antibody, Pig7 antibody, TNF-alpha antibody, 3222402J11Rik antibody, C85531 antibody, N4WBP3 antibody, TBX1 antibody, lipopolysaccharide induced TNF factor antibody, lipopolysaccharide-induced TNF factor antibody, LPS-induced TN factor antibody, LITAF antibody, Litaf antibody
- Background
- Lipopolysaccharide is a potent stimulator of monocytes and macrophages, causing secretion of tumor necrosis factor-alpha (TNF-alpha) and other inflammatory mediators. This gene encodes lipopolysaccharide-induced TNF-alpha factor, which is a DNA-binding protein and can mediate the TNF-alpha expression by direct binding to the promoter region of the TNF-alpha gene. The transcription of this gene is induced by tumor suppressor p53 and has been implicated in the p53-induced apoptotic pathway. Mutations in this gene cause Charcot-Marie-Tooth disease type 1C (CMT1C) and may be involved in the carcinogenesis of extramammary Paget's disease (EMPD). Multiple alternatively spliced transcript variants have been found for this gene.
- Molecular Weight
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Observed_MW: 20 kDa
Calculated_MW: 15 kDa/17 kDa/23 kDa
- Gene ID
- 9516
- UniProt
- Q99732
- Pathways
- Cellular Response to Molecule of Bacterial Origin
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