Phone:
+1 877 302 8632
Fax:
+1 888 205 9894 (Toll-free)
E-Mail:
orders@antibodies-online.com

MCM10 antibody

MCM10 Reactivity: Human, Mouse IF Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN7261385
  • Target See all MCM10 Antibodies
    MCM10 (Minichromosome Maintenance Deficient 10 (MCM10))
    Reactivity
    • 25
    • 8
    • 5
    • 4
    • 3
    • 3
    • 3
    • 1
    • 1
    • 1
    • 1
    Human, Mouse
    Host
    • 24
    • 1
    Rabbit
    Clonality
    • 25
    Polyclonal
    Conjugate
    • 18
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This MCM10 antibody is un-conjugated
    Application
    • 16
    • 5
    • 4
    • 3
    • 2
    • 1
    Immunofluorescence (IF)
    Characteristics
    Polyclonal Antibody
    Purification
    Affinity purification
    Immunogen
    Recombinant fusion protein of human MCM10 (NP_877428.1).
    Isotype
    IgG
    Top Product
    Discover our top product MCM10 Primary Antibody
  • Application Notes
    IF 1:50-1:200
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    1 mg/mL
    Buffer
    PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Storage
    -20 °C
    Storage Comment
    Store at -20°C. Avoid freeze / thaw cycles.
  • Target
    MCM10 (Minichromosome Maintenance Deficient 10 (MCM10))
    Alternative Name
    MCM10 (MCM10 Products)
    Synonyms
    CG9241 antibody, DmMCM10 antibody, Dmel\\CG9241 antibody, Scim19 antibody, mcm10 antibody, CNA43 antibody, DNA43 antibody, xmcm10 antibody, 2410041F14Rik antibody, AU018508 antibody, C330019M07Rik antibody, C79164 antibody, Minichromosome maintenance 10 antibody, minichromosome maintenance 10 replication initiation factor antibody, minichromosome maintenance 10 replication initiation factor L homeolog antibody, Mcm10 antibody, MCM10 antibody, mcm10.L antibody
    Background
    The protein encoded by this gene is one of the highly conserved mini-chromosome maintenance proteins (MCM) that are involved in the initiation of eukaryotic genome replication. The hexameric protein complex formed by MCM proteins is a key component of the pre-replication complex (pre-RC) and it may be involved in the formation of replication forks and in the recruitment of other DNA replication related proteins. This protein can interact with MCM2 and MCM6, as well as with the origin recognition protein ORC2. It is regulated by proteolysis and phosphorylation in a cell cycle-dependent manner. Studies of a similar protein in Xenopus suggest that the chromatin binding of this protein at the onset of DNA replication is after pre-RC assembly and before origin unwinding. Alternatively spliced transcript variants encoding distinct isoforms have been identified.
    Gene ID
    55388
    UniProt
    Q7L590
    Pathways
    Mitotic G1-G1/S Phases, DNA Replication
You are here:
Support