ORC6 antibody

Catalog No. ABIN7261383

Product Details anti-ORC6 Antibody

Target: ORC6 (Origin Recognition Complex, Subunit 6 (ORC6))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This ORC6 antibody is un-conjugated

Application: Immunofluorescence (IF)

Characteristics: Polyclonal Antibody

Purification: Affinity purification

Immunogen: Recombinant fusion protein of human ORC6 (NP_055136.1).

Isotype: IgG

Application Details

Application Notes: IF 1:50-1:200

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for ORC6

Target: ORC6 (Origin Recognition Complex, Subunit 6 (ORC6))

Alternative Name: ORC6 (ORC6 Products)

Synonyms: Orc6l antibody, CG1584 antibody, DmORC 6 antibody, DmORC6 antibody, Dmel\\CG1584 antibody, ORC antibody, ORC6 antibody, orc6 antibody, rDmORC antibody, ORC6L antibody, ARABIDOPSIS THALIANA ORIGIN RECOGNITION COMPLEX PROTEIN 6 antibody, ATORC6 antibody, ORIGIN RECOGNITION COMPLEX SUBUNIT 6 antibody, T2P11.3 antibody, T2P11_3 antibody, origin recognition complex protein 6 antibody, DDBDRAFT_0186183 antibody, DDBDRAFT_0233113 antibody, DDB_0186183 antibody, DDB_0233113 antibody, LOC100284755 antibody, orc6l antibody, 6720420I10Rik antibody, origin recognition complex, subunit 6 antibody, Origin recognition complex subunit 6 antibody, origin recognition complex subunit 6 antibody, origin recognition complex protein 6 antibody, origin recognition complex subunit Orc6 antibody, Orc6 antibody, ORC6 antibody, CpipJ_CPIJ005016 antibody, SJAG_01267 antibody, orcF antibody, LOC100284755 antibody, orc6 antibody

Background: The origin recognition complex (ORC) is a highly conserved six subunit protein complex essential for the initiation of the DNA replication in eukaryotic cells. Studies in yeast demonstrated that ORC binds specifically to origins of replication and serves as a platform for the assembly of additional initiation factors such as Cdc6 and Mcm proteins. The protein encoded by this gene is a subunit of the ORC complex. Gene silencing studies with small interfering RNA demonstrated that this protein plays an essential role in coordinating chromosome replication and segregation with cytokinesis.

Gene ID: 23594

UniProt: Q9Y5N6

Pathways: Mitotic G1-G1/S Phases, DNA Replication, M Phase, Synthesis of DNA