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BAF53A antibody

BAF53A Reactivity: Human, Mouse WB Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN7261339
  • Target See all BAF53A Antibodies
    BAF53A (Actin-Like 6A (BAF53A))
    Reactivity
    • 64
    • 56
    • 38
    • 7
    • 7
    • 5
    • 5
    • 4
    • 4
    • 4
    • 2
    • 2
    • 1
    • 1
    • 1
    Human, Mouse
    Host
    • 71
    • 2
    Rabbit
    Clonality
    • 62
    • 11
    Polyclonal
    Conjugate
    • 38
    • 5
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This BAF53A antibody is un-conjugated
    Application
    • 56
    • 24
    • 13
    • 13
    • 10
    • 5
    • 5
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB)
    Characteristics
    Polyclonal Antibody
    Purification
    Affinity purification
    Immunogen
    Recombinant fusion protein of human ACTL6A (NP_004292.1).
    Isotype
    IgG
    Top Product
    Discover our top product BAF53A Primary Antibody
  • Application Notes
    WB 1:500-1:2000
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    1 mg/mL
    Buffer
    PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Storage
    -20 °C
    Storage Comment
    Store at -20°C. Avoid freeze / thaw cycles.
  • Target
    BAF53A (Actin-Like 6A (BAF53A))
    Alternative Name
    ACTL6A (BAF53A Products)
    Background
    This gene encodes a family member of actin-related proteins (ARPs), which share significant amino acid sequence identity to conventional actins. Both actins and ARPs have an actin fold, which is an ATP-binding cleft, as a common feature. The ARPs are involved in diverse cellular processes, including vesicular transport, spindle orientation, nuclear migration and chromatin remodeling. This gene encodes a 53 kDa subunit protein of the BAF (BRG1/brm-associated factor) complex in mammals, which is functionally related to SWI/SNF complex in S. cerevisiae and Drosophila, the latter is thought to facilitate transcriptional activation of specific genes by antagonizing chromatin-mediated transcriptional repression. Together with beta-actin, it is required for maximal ATPase activity of BRG1, and for the association of the BAF complex with chromatin/matrix. Three transcript variants that encode two different protein isoforms have been described.
    Molecular Weight

    Observed_MW: 48 kDa

    Calculated_MW: 43 kDa/47 kDa

    Gene ID
    86
    UniProt
    O96019
    Pathways
    Chromatin Binding, Photoperiodism
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