PSMD9 antibody

Catalog No. ABIN7261303

Product Details anti-PSMD9 Antibody

Target: PSMD9 (Proteasome (Prosome, Macropain) 26S Subunit, Non-ATPase, 9 (PSMD9))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This PSMD9 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF)

Characteristics: Polyclonal Antibody

Purification: Affinity purification

Immunogen: Recombinant fusion protein of human PSMD9 (NP_002804.2).

Isotype: IgG

Application Details

Application Notes: WB 1:500-1:2000 IHC 1:50-1:200 IF 1:50-1:200

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for PSMD9

Target: PSMD9 (Proteasome (Prosome, Macropain) 26S Subunit, Non-ATPase, 9 (PSMD9))

Alternative Name: PSMD9 (PSMD9 Products)

Synonyms: Rpn4 antibody, p27 antibody, Bridge antibody, Bridge-1 antibody, zgc:92643 antibody, wu:fb30g07 antibody, PSMD9 antibody, psmd9 antibody, DDBDRAFT_0202482 antibody, DDBDRAFT_0232989 antibody, DDB_0202482 antibody, DDB_0232989 antibody, 1500011J20Rik antibody, 2610202L11Rik antibody, P27 antibody, proteasome 26S subunit, non-ATPase 9 antibody, proteasome 26S subunit, non-ATPase 9 L homeolog antibody, 26S proteasome non-ATPase regulatory subunit 9 antibody, proteasome (prosome, macropain) 26S subunit, non-ATPase, 9 antibody, PSMD9 antibody, Psmd9 antibody, psmd9 antibody, psmd9.L antibody, psmD9 antibody

Background: The 26S proteasome is a multicatalytic proteinase complex with a highly ordered structure composed of 2 complexes, a 20S core and a 19S regulator. The 20S core is composed of 4 rings of 28 non-identical subunits, 2 rings are composed of 7 alpha subunits and 2 rings are composed of 7 beta subunits. The 19S regulator is composed of a base, which contains 6 ATPase subunits and 2 non-ATPase subunits, and a lid, which contains up to 10 non-ATPase subunits. Proteasomes are distributed throughout eukaryotic cells at a high concentration and cleave peptides in an ATP/ubiquitin-dependent process in a non-lysosomal pathway. An essential function of a modified proteasome, the immunoproteasome, is the processing of class I MHC peptides. This gene encodes a non-ATPase subunit of the 19S regulator. Three transcript variants encoding two different isoforms have been found for this gene.

Molecular Weight:

Observed_MW: 25 kDa

Calculated_MW: 13 kDa/22 kDa/24 kDa

Gene ID: 5715

UniProt: O00233

Pathways: Positive Regulation of Peptide Hormone Secretion, Negative Regulation of Hormone Secretion, Mitotic G1-G1/S Phases, DNA Replication, Synthesis of DNA, Ubiquitin Proteasome Pathway