BAIAP2 antibody

Catalog No. ABIN7261289

Product Details anti-BAIAP2 Antibody

Target: BAIAP2 (BAI1-Associated Protein 2 (BAIAP2))

Reactivity: Human, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This BAIAP2 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Characteristics: Polyclonal Antibody

Purification: Affinity purification

Immunogen: Recombinant fusion protein of human BAIAP2 (NP_059344.1).

Isotype: IgG

Application Details

Application Notes: WB 1:500-1:2000 IHC 1:50-1:200

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for BAIAP2

Target: BAIAP2 (BAI1-Associated Protein 2 (BAIAP2))

Alternative Name: BAIAP2 (BAIAP2 Products)

Synonyms: BAP2 antibody, FLAF3 antibody, IRSP53 antibody, CG-ALPHA antibody, FSHA antibody, GPHA1 antibody, GPHa antibody, HCG antibody, LHA antibody, TSHA antibody, IRSP53S antibody, BAIAP2 antibody, DKFZp470L1727 antibody, IRSp53 antibody, R75030 antibody, Irsp53 antibody, wu:fk29g02 antibody, zgc:136827 antibody, BAI1 associated protein 2 antibody, glycoprotein hormones, alpha polypeptide antibody, BAI1-associated protein 2 antibody, brain-specific angiogenesis inhibitor 1-associated protein 2 antibody, BAI1-associated protein 2a antibody, BAIAP2 antibody, CGA antibody, baiap2 antibody, Baiap2 antibody, baiap2a antibody

Background: The protein encoded by this gene has been identified as a brain-specific angiogenesis inhibitor (BAI1)-binding protein. This adaptor protein links membrane bound G-proteins to cytoplasmic effector proteins. This protein functions as an insulin receptor tyrosine kinase substrate and suggests a role for insulin in the central nervous system. It also associates with a downstream effector of Rho small G proteins, which is associated with the formation of stress fibers and cytokinesis. This protein is involved in lamellipodia and filopodia formation in motile cells and may affect neuronal growth-cone guidance. This protein has also been identified as interacting with the dentatorubral-pallidoluysian atrophy gene, which is associated with an autosomal dominant neurodegenerative disease. Alternative splicing results in multiple transcript variants encoding distinct isoforms.

Molecular Weight:

Observed_MW: 61-65 kDa

Calculated_MW: 56 kDa/57 kDa/59 kDa/60 kDa

Gene ID: 10458

UniProt: Q9UQB8