Glutaredoxin 1 antibody

Catalog No. ABIN7261263

Product Details anti-Glutaredoxin 1 Antibody

Target: Glutaredoxin 1 (GRX1)

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Glutaredoxin 1 antibody is un-conjugated

Application: Immunohistochemistry (IHC), Immunofluorescence (IF)

Characteristics: Polyclonal Antibody

Purification: Affinity purification

Immunogen: Recombinant fusion protein of human GLRX (NP_001112362.1).

Isotype: IgG

Application Details

Application Notes: IHC 1:50-1:200 IF 1:50-1:200

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for Glutaredoxin 1

Target: Glutaredoxin 1 (GRX1)

Alternative Name: GLRX (GRX1 Products)

Synonyms: Glrx1 antibody, Grx antibody, grx antibody, wu:fc38f02 antibody, zgc:103707 antibody, GLRXL antibody, Grx1 antibody, TTase antibody, C86710 antibody, D13Wsu156e antibody, grx1 antibody, GLRX antibody, GRX antibody, GRX1 antibody, GLRX1 antibody, TTF antibody, glrx antibody, glutaredoxin antibody, glutaredoxin (thioltransferase) antibody, glutaredoxin Grx1 antibody, NrdH-redoxin antibody, Uncharacterized monothiol glutaredoxin F10D7.3 antibody, glutaredoxin-1 (Grx1) antibody, temporal expression: late antibody, glutaredoxin L homeolog antibody, Glrx antibody, glrx antibody, GLRX antibody, grx1 antibody, AF_RS07750 antibody, F10D7.3 antibody, AFUA_1G06100 antibody, NT01EI_2528 antibody, O2L antibody, glrx.L antibody

Target Type: Viral Protein

Background: This gene encodes a member of the glutaredoxin family. The encoded protein is a cytoplasmic enzyme catalyzing the reversible reduction of glutathione-protein mixed disulfides. This enzyme highly contributes to the antioxidant defense system. It is crucial for several signalling pathways by controlling the S-glutathionylation status of signalling mediators. It is involved in beta-amyloid toxicity and Alzheimer's disease. Multiple alternatively spliced transcript variants encoding the same protein have been identified.

Gene ID: 2745

UniProt: P35754

Pathways: Cell RedoxHomeostasis