SPTBN1 antibody

Catalog No. ABIN7261215

Product Details anti-SPTBN1 Antibody

Target: SPTBN1 (Spectrin Beta, Non-Erythrocytic 1 (SPTBN1))

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This SPTBN1 antibody is un-conjugated

Application: Western Blotting (WB)

Characteristics: Polyclonal Antibody

Purification: Affinity purification

Immunogen: Recombinant fusion protein of human SPTBN1 (NP_003119.2).

Isotype: IgG

Application Details

Application Notes: WB 1:1000-1:3000

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for SPTBN1

Target: SPTBN1 (Spectrin Beta, Non-Erythrocytic 1 (SPTBN1))

Alternative Name: SPTBN1 (SPTBN1 Products)

Synonyms: 9930031C03Rik antibody, AL033301 antibody, SPTB2 antibody, Spnb-2 antibody, Spnb2 antibody, elf1 antibody, elf3 antibody, mKIAA4049 antibody, ELF antibody, betaSpII antibody, Spnb1 antibody, spectrin beta, non-erythrocytic 1 antibody, spectrin, beta, non-erythrocytic 1 antibody, Sptbn1 antibody, SPTBN1 antibody

Background: Spectrin is an actin crosslinking and molecular scaffold protein that links the plasma membrane to the actin cytoskeleton, and functions in the determination of cell shape, arrangement of transmembrane proteins, and organization of organelles. It is composed of two antiparallel dimers of alpha- and beta- subunits. This gene is one member of a family of beta-spectrin genes. The encoded protein contains an N-terminal actin-binding domain, and 17 spectrin repeats which are involved in dimer formation. Multiple transcript variants encoding different isoforms have been found for this gene.

Molecular Weight:

Observed_MW: 275 kDa

Calculated_MW: 251 kDa/253 kDa/274 kDa

Gene ID: 6711

UniProt: Q01082

Pathways: Regulation of Actin Filament Polymerization, Protein targeting to Nucleus