RBM15 antibody
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- Target See all RBM15 Antibodies
- RBM15 (RNA Binding Motif Protein 15 (RBM15))
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Reactivity
- Human, Mouse
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Host
- Rabbit
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Clonality
- Polyclonal
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Conjugate
- This RBM15 antibody is un-conjugated
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Application
- Western Blotting (WB)
- Characteristics
- Polyclonal Antibody
- Purification
- Affinity purification
- Immunogen
- Recombinant fusion protein of human RBM15 (NP_001188474.1).
- Isotype
- IgG
- Top Product
- Discover our top product RBM15 Primary Antibody
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- Application Notes
- WB 1:500-1:2000
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 1 mg/mL
- Buffer
- PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3
- Preservative
- Sodium azide
- Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Storage
- -20 °C
- Storage Comment
- Store at -20°C. Avoid freeze / thaw cycles.
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- Target
- RBM15 (RNA Binding Motif Protein 15 (RBM15))
- Alternative Name
- RBM15 (RBM15 Products)
- Synonyms
- MGC83913 antibody, im:7139999 antibody, OTT antibody, OTT1 antibody, SPEN antibody, C230088J01Rik antibody, mKIAA1438 antibody, RNA binding motif protein 15 antibody, RNA binding motif protein 15 S homeolog antibody, RBM15 antibody, rbm15.S antibody, rbm15 antibody, Rbm15 antibody
- Background
- RNA-binding motif protein 15 (RBM15) belongs to the SPEN protein family,which have repressor function in several signaling pathway,and may bind to RNA through interaction with spliceosome components. It was first described as a 5' translocation partner of the MAL gene in t(1,22)(p13,q13) infant acute megakaryocytic leukemia,and it functions in murine hematopoiesis through modulating Notch-induced transcriptional activation,which play crucial roles in leukemogenesis. Decreasing RBM15 levels with RNA interference could inhibit the growth and proliferation,block the cell cycle,and induce apoptosis in CML cells.
- Molecular Weight
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Observed_MW: 120 kDa
Calculated_MW: 99 kDa/104 kDa/106 kDa/107 kDa
- Gene ID
- 64783
- UniProt
- Q96T37
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