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RBM15 antibody

RBM15 Reactivity: Human, Mouse WB Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN7261163
  • Target See all RBM15 Antibodies
    RBM15 (RNA Binding Motif Protein 15 (RBM15))
    Reactivity
    • 31
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    Human, Mouse
    Host
    • 25
    • 6
    Rabbit
    Clonality
    • 27
    • 4
    Polyclonal
    Conjugate
    • 17
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This RBM15 antibody is un-conjugated
    Application
    • 15
    • 13
    • 13
    • 8
    • 7
    • 5
    • 4
    • 4
    • 3
    • 3
    • 1
    • 1
    Western Blotting (WB)
    Characteristics
    Polyclonal Antibody
    Purification
    Affinity purification
    Immunogen
    Recombinant fusion protein of human RBM15 (NP_001188474.1).
    Isotype
    IgG
    Top Product
    Discover our top product RBM15 Primary Antibody
  • Application Notes
    WB 1:500-1:2000
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    1 mg/mL
    Buffer
    PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Storage
    -20 °C
    Storage Comment
    Store at -20°C. Avoid freeze / thaw cycles.
  • Target
    RBM15 (RNA Binding Motif Protein 15 (RBM15))
    Alternative Name
    RBM15 (RBM15 Products)
    Synonyms
    MGC83913 antibody, im:7139999 antibody, OTT antibody, OTT1 antibody, SPEN antibody, C230088J01Rik antibody, mKIAA1438 antibody, RNA binding motif protein 15 antibody, RNA binding motif protein 15 S homeolog antibody, RBM15 antibody, rbm15.S antibody, rbm15 antibody, Rbm15 antibody
    Background
    RNA-binding motif protein 15 (RBM15) belongs to the SPEN protein family,which have repressor function in several signaling pathway,and may bind to RNA through interaction with spliceosome components. It was first described as a 5' translocation partner of the MAL gene in t(1,22)(p13,q13) infant acute megakaryocytic leukemia,and it functions in murine hematopoiesis through modulating Notch-induced transcriptional activation,which play crucial roles in leukemogenesis. Decreasing RBM15 levels with RNA interference could inhibit the growth and proliferation,block the cell cycle,and induce apoptosis in CML cells.
    Molecular Weight

    Observed_MW: 120 kDa

    Calculated_MW: 99 kDa/104 kDa/106 kDa/107 kDa

    Gene ID
    64783
    UniProt
    Q96T37
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