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HBEGF antibody (AA 51-150)

HBEGF Reactivity: Human, Mouse, Rat ELISA, IF (cc), IHC (p) Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN701050
  • Target See all HBEGF Antibodies
    HBEGF (Heparin-Binding EGF-Like Growth Factor (HBEGF))
    Binding Specificity
    • 15
    • 14
    • 14
    • 8
    • 7
    • 7
    • 6
    • 4
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 51-150
    Reactivity
    • 74
    • 19
    • 18
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    Human, Mouse, Rat
    Host
    • 68
    • 9
    Rabbit
    Clonality
    • 66
    • 10
    • 1
    Polyclonal
    Conjugate
    • 25
    • 10
    • 7
    • 5
    • 4
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    This HBEGF antibody is un-conjugated
    Application
    • 34
    • 28
    • 25
    • 15
    • 13
    • 10
    • 7
    • 7
    • 6
    • 6
    • 3
    • 3
    • 3
    • 2
    • 2
    • 1
    ELISA, Immunofluorescence (Cultured Cells) (IF (cc)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
    Cross-Reactivity
    Human, Mouse, Rat
    Predicted Reactivity
    Dog,Cow,Pig,Horse,Chicken,Rabbit
    Purification
    Purified by Protein A.
    Immunogen
    KLH conjugated synthetic peptide derived from human HB-EGF/DTSF
    Isotype
    IgG
  • Application Notes
    ELISA 1:500-1000
    IHC-P 1:200-400
    IF(ICC) 1:50-200
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    1 μg/μL
    Buffer
    0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.
    Preservative
    ProClin
    Precaution of Use
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
    Storage
    4 °C,-20 °C
    Storage Comment
    Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.
    Expiry Date
    12 months
  • Lebkuechner, Wilhelmsson, Möllerström, Pekna, Pekny: "Heterogeneity of Notch signaling in astrocytes and the effects of GFAP and vimentin deficiency." in: Journal of neurochemistry, (2015) (PubMed).

  • Target
    HBEGF (Heparin-Binding EGF-Like Growth Factor (HBEGF))
    Alternative Name
    HB-EGF (HBEGF Products)
    Synonyms
    hbegf antibody, zgc:165443 antibody, HBEGF antibody, zgc:175091 antibody, DTR antibody, DTS antibody, DTSF antibody, HEGFL antibody, Dtr antibody, GFHB antibody, Hb-egf antibody, Hegfl antibody, AW047313 antibody, Dts antibody, HB-EGF antibody, heparin-binding EGF-like growth factor b antibody, heparin binding EGF like growth factor antibody, Heparin-binding EGF-like growth factor antibody, heparin-binding EGF-like growth factor a antibody, heparin-binding EGF-like growth factor antibody, hbegfb antibody, HBEGF antibody, hbegf antibody, hbegfa antibody, Hbegf antibody
    Background

    Synonyms: DTR, DTS, DTSF, HEGFL, Proheparin-binding EGF-like growth factor, HBEGF

    Background: Growth factor that mediates its effects via EGFR, ERBB2 and ERBB4. Required for normal cardiac valve formation and normal heart function. Promotes smooth muscle cell proliferation. May be involved in macrophage-mediated cellular proliferation. It is mitogenic for fibroblasts, but not endothelial cells. It is able to bind EGF receptor/EGFR with higher affinity than EGF itself and is a far more potent mitogen for smooth muscle cells than EGF. Also acts as a diphtheria toxin receptor.

    Gene ID
    1839
    UniProt
    Q99075
    Pathways
    RTK Signaling, Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway
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