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PIDD antibody

PIDD Reactivity: Human, Rat, Mouse IHC, WB, IF Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN7261141
  • Target See all PIDD Antibodies
    PIDD (P53-Induced Death Domain Protein (PIDD))
    Reactivity
    • 19
    • 19
    • 7
    • 2
    • 1
    • 1
    • 1
    • 1
    Human, Rat, Mouse
    Host
    • 33
    • 3
    Rabbit
    Clonality
    • 33
    • 3
    Polyclonal
    Conjugate
    • 15
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This PIDD antibody is un-conjugated
    Application
    • 13
    • 13
    • 12
    • 6
    • 5
    • 4
    • 3
    • 2
    • 2
    • 1
    Immunohistochemistry (IHC), Western Blotting (WB), Immunofluorescence (IF)
    Characteristics
    Polyclonal Antibody
    Purification
    Affinity purification
    Immunogen
    Recombinant fusion protein of human PIDD (NP_665893.2).
    Isotype
    IgG
    Top Product
    Discover our top product PIDD Primary Antibody
  • Application Notes
    WB 1:500-1:1000 IHC 1:50-1:200 IF 1:50-1:100
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    1 mg/mL
    Buffer
    PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Storage
    -20 °C
    Storage Comment
    Store at -20°C. Avoid freeze / thaw cycles.
  • Target
    PIDD (P53-Induced Death Domain Protein (PIDD))
    Alternative Name
    PIDD (PIDD Products)
    Synonyms
    1200011D09Rik antibody, AU042446 antibody, Pidd antibody, LRDD antibody, Lrdd antibody, p53 induced death domain protein 1 antibody, p53-induced death domain protein 1 antibody, Pidd1 antibody, PIDD1 antibody
    Background
    The protein encoded by this gene contains a leucine-rich repeat and a death domain. This protein has been shown to interact with other death domain proteins, such as Fas (TNFRSF6)-associated via death domain (FADD) and MAP-kinase activating death domain-containing protein (MADD), and thus may function as an adaptor protein in cell death-related signaling processes. The expression of the mouse counterpart of this gene has been found to be positively regulated by the tumor suppressor p53 and to induce cell apoptosis in response to DNA damage, which suggests a role for this gene as an effector of p53-dependent apoptosis. Alternative splicing results in multiple transcript variants.
    Molecular Weight

    Observed_MW: 100-110 kDa

    Calculated_MW: 33 kDa/37 kDa/58 kDa/66 kDa/82 kDa/97 kDa/99 kDa

    Gene ID
    55367
    UniProt
    Q9HB75
    Pathways
    p53 Signaling, Caspase Cascade in Apoptosis, Positive Regulation of Endopeptidase Activity
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