PIDD antibody
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- Target See all PIDD Antibodies
- PIDD (P53-Induced Death Domain Protein (PIDD))
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Reactivity
- Human, Rat, Mouse
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Host
- Rabbit
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Clonality
- Polyclonal
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Conjugate
- This PIDD antibody is un-conjugated
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Application
- Immunohistochemistry (IHC), Western Blotting (WB), Immunofluorescence (IF)
- Characteristics
- Polyclonal Antibody
- Purification
- Affinity purification
- Immunogen
- Recombinant fusion protein of human PIDD (NP_665893.2).
- Isotype
- IgG
- Top Product
- Discover our top product PIDD Primary Antibody
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- Application Notes
- WB 1:500-1:1000 IHC 1:50-1:200 IF 1:50-1:100
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 1 mg/mL
- Buffer
- PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3
- Preservative
- Sodium azide
- Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Storage
- -20 °C
- Storage Comment
- Store at -20°C. Avoid freeze / thaw cycles.
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- Target
- PIDD (P53-Induced Death Domain Protein (PIDD))
- Alternative Name
- PIDD (PIDD Products)
- Synonyms
- 1200011D09Rik antibody, AU042446 antibody, Pidd antibody, LRDD antibody, Lrdd antibody, p53 induced death domain protein 1 antibody, p53-induced death domain protein 1 antibody, Pidd1 antibody, PIDD1 antibody
- Background
- The protein encoded by this gene contains a leucine-rich repeat and a death domain. This protein has been shown to interact with other death domain proteins, such as Fas (TNFRSF6)-associated via death domain (FADD) and MAP-kinase activating death domain-containing protein (MADD), and thus may function as an adaptor protein in cell death-related signaling processes. The expression of the mouse counterpart of this gene has been found to be positively regulated by the tumor suppressor p53 and to induce cell apoptosis in response to DNA damage, which suggests a role for this gene as an effector of p53-dependent apoptosis. Alternative splicing results in multiple transcript variants.
- Molecular Weight
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Observed_MW: 100-110 kDa
Calculated_MW: 33 kDa/37 kDa/58 kDa/66 kDa/82 kDa/97 kDa/99 kDa
- Gene ID
- 55367
- UniProt
- Q9HB75
- Pathways
- p53 Signaling, Caspase Cascade in Apoptosis, Positive Regulation of Endopeptidase Activity
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