RNMTL1 antibody

Catalog No. ABIN7261137

Product Details anti-RNMTL1 Antibody

Target: RNMTL1 (RNA Methyltransferase Like 1 (RNMTL1))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This RNMTL1 antibody is un-conjugated

Application: Western Blotting (WB)

Characteristics: Polyclonal Antibody

Purification: Affinity purification

Immunogen: Recombinant fusion protein of human MRM3 (NP_060616.1).

Isotype: IgG

Application Details

Application Notes: WB 1:500-1:2000

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for RNMTL1

Target: RNMTL1 (RNA Methyltransferase Like 1 (RNMTL1))

Alternative Name: MRM3 (RNMTL1 Products)

Background: Efficient translation of mitochondrial-derived transcripts requires proper assembly of the large subunit of the mitochondrial ribosome. Central to the biogenesis of this large subunit is the A-loop of mitochondrial 16S rRNA, which is modified by three rRNA methyltransferases located near mtDNA nucleoids. The protein encoded by this gene methylates G(1370) of 16S rRNA, and this modification is necessary for proper ribosomal large subnit assembly. Two transcript variants encoding different isoforms have been found for this gene.

Molecular Weight:

Observed_MW: 47 kDa

Calculated_MW: 47 kDa

Gene ID: 55178

UniProt: Q9HC36