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NBR1 antibody
NBR1
Reactivity: Human, Mouse, Rat, Monkey
IHC
Host: Rabbit
Polyclonal
unconjugated
Product Details anti-NBR1 Antibody
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Target
See all NBR1 Antibodies
NBR1
(Neighbor of BRCA1 Gene 1 (NBR1))
Reactivity
All reactivities for NBR1 antibodies
Human, Mouse, Rat, Monkey
Host
All hosts for NBR1 antibodies
Rabbit
Clonality
All clonalities for NBR1 antibodies
Polyclonal
Conjugate
All conjugates for NBR1 antibodies
This NBR1 antibody is un-conjugated
Application
All applications for NBR1 antibodies
Immunohistochemistry (IHC)
Characteristics
Polyclonal Antibody
Purification
Affinity purification
Immunogen
Recombinant protein of human NBR1
Isotype
IgG
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Alternatives
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Application Details
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Application Notes
IHC 1:50-1:200
Restrictions
For Research Use only
Handling
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Format
Liquid
Concentration
1 mg/mL
Buffer
PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3
Preservative
Sodium azide
Precaution of Use
This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage
-20 °C
Storage Comment
Store at -20°C. Avoid freeze / thaw cycles.
Target Details for NBR1
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Target
NBR1
(Neighbor of BRCA1 Gene 1 (NBR1))
Alternative Name
NBR1 (NBR1 Products )
Synonyms
fa99f08 antibody, wu:fa99f08 antibody, MGC69008 antibody, NBR1 antibody, 1A1-3B antibody, M17S2 antibody, mKIAA0049 antibody, Ca125 antibody, RGD1311421 antibody, neighbor of brca1 gene 1a antibody, neighbor of BRCA1 gene 1 L homeolog antibody, NBR1, autophagy cargo receptor antibody, neighbor of Brca1 gene 1 antibody, nbr1a antibody, nbr1.L antibody, NBR1 antibody, Nbr1 antibody
Background
The protein encoded by this gene was originally identified as an ovarian tumor antigen monitored in ovarian cancer. The encoded protein contains a B-box/coiled-coil motif, which is present in many genes with transformation potential. It functions as a specific autophagy receptor for the selective autophagic degradation of peroxisomes by forming intracellular inclusions with ubiquitylated autophagic substrates. This gene is located on a region of chromosome 17q21.1 that is in close proximity to the BRCA1 tumor suppressor gene. Alternative splicing of this gene results in multiple transcript variants.
Gene ID
4077
UniProt
Q14596
Pathways
Autophagy
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