CSTB antibody
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- Target See all CSTB Antibodies
- CSTB (Cystatin B (Stefin B) (CSTB))
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Reactivity
- Human, Rat
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Host
- Rabbit
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Clonality
- Polyclonal
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Conjugate
- This CSTB antibody is un-conjugated
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Application
- Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF)
- Characteristics
- Polyclonal Antibody
- Purification
- Affinity purification
- Immunogen
- Recombinant fusion protein of human CSTB (NP_000091.1).
- Isotype
- IgG
- Top Product
- Discover our top product CSTB Primary Antibody
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anti-Cystatin B (Stefin B) (CSTB) (AA 1-98) antibody
CSTB Reactivity: Human WB, IHC, ELISA, IF, IP Host: Rabbit Polyclonal unconjugated
anti-Cystatin B (Stefin B) (CSTB) (C-Term) antibodyCSTB Reactivity: Human, Rat, Mouse WB, IHC, ELISA, IF, ICC Host: Rabbit Polyclonal unconjugated
anti-Cystatin B (Stefin B) (CSTB) (AA 1-98) antibodyCSTB Reactivity: Human WB, ELISA, IF, IHC (p) Host: Mouse Monoclonal M2-F1 unconjugated
anti-Cystatin B (Stefin B) (CSTB) (C-Term) antibodyVerified CSTB Reactivity: Human WB, IHC, ELISA Host: Goat Polyclonal unconjugated
anti-Cystatin B (Stefin B) (CSTB) (AA 1-98) antibodyCSTB Reactivity: Human WB, ELISA, IHC (p) Host: Mouse Monoclonal M1-C1 unconjugated
anti-Cystatin B (Stefin B) (CSTB) (AA 2-98) antibodyCSTB Reactivity: Rat WB, IHC, IP, ICC Host: Mouse Monoclonal C13 unconjugated
anti-Cystatin B (Stefin B) (CSTB) (AA 1-98) antibodyCSTB Reactivity: Human WB, IHC, ICC Host: Rabbit Polyclonal unconjugated
anti-Cystatin B (Stefin B) (CSTB) (AA 2-98) antibodyCSTB Reactivity: Rat WB, IHC, IP, ICC Host: Mouse Monoclonal C10 unconjugated
anti-Cystatin B (Stefin B) (CSTB) (AA 51-98) antibodyCSTB Reactivity: Human ELISA, IHC (p), IF (cc), IF (p), IHC (fro) Host: Rabbit Polyclonal unconjugated
anti-Cystatin B (Stefin B) (CSTB) antibodyCSTB Reactivity: Human IF, ICC, IHC (p) Host: Rabbit Polyclonal unconjugated
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- Application Notes
- WB 1:500-1:2000 IHC 1:50-1:200 IF 1:50-1:200
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 1 mg/mL
- Buffer
- PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3
- Preservative
- Sodium azide
- Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Storage
- -20 °C
- Storage Comment
- Store at -20°C. Avoid freeze / thaw cycles.
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- Target
- CSTB (Cystatin B (Stefin B) (CSTB))
- Alternative Name
- CSTB (CSTB Products)
- Background
- The cystatin superfamily encompasses proteins that contain multiple cystatin-like sequences. Some of the members are active cysteine protease inhibitors, while others have lost or perhaps never acquired this inhibitory activity. There are three inhibitory families in the superfamily, including the type 1 cystatins (stefins), type 2 cystatins and kininogens. This gene encodes a stefin that functions as an intracellular thiol protease inhibitor. The protein is able to form a dimer stabilized by noncovalent forces, inhibiting papain and cathepsins l, h and b. The protein is thought to play a role in protecting against the proteases leaking from lysosomes. Evidence indicates that mutations in this gene are responsible for the primary defects in patients with progressive myoclonic epilepsy (EPM1). One type of mutation responsible for EPM1 is the expansion in the promoter region of this gene of a CCCCGCCCCGCG repeat from 2-3 copies to 30-78 copies.
- Molecular Weight
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Observed_MW: 14 kDa
Calculated_MW: 11 kDa
- Gene ID
- 1476
- UniProt
- P04080
- Pathways
- Response to Water Deprivation
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