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APLP1 antibody

APLP1 Reactivity: Human, Mouse, Rat WB, IHC Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN7260605
  • Target See all APLP1 Antibodies
    APLP1 (Amyloid beta (A4) Precursor-Like Protein 1 (APLP1))
    Reactivity
    • 32
    • 30
    • 14
    • 5
    • 4
    • 2
    • 1
    Human, Mouse, Rat
    Host
    • 43
    • 2
    Rabbit
    Clonality
    • 44
    • 1
    Polyclonal
    Conjugate
    • 13
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This APLP1 antibody is un-conjugated
    Application
    • 31
    • 13
    • 13
    • 8
    • 6
    • 4
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB), Immunohistochemistry (IHC)
    Characteristics
    Polyclonal Antibody
    Purification
    Affinity purification
    Immunogen
    Recombinant fusion protein of human APLP1 (NP_005157.1).
    Isotype
    IgG
    Top Product
    Discover our top product APLP1 Primary Antibody
  • Application Notes
    WB 1:500-1:2000 IHC 1:50-1:100
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    1 mg/mL
    Buffer
    PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Storage
    -20 °C
    Storage Comment
    Store at -20°C. Avoid freeze / thaw cycles.
  • Target
    APLP1 (Amyloid beta (A4) Precursor-Like Protein 1 (APLP1))
    Alternative Name
    APLP1 (APLP1 Products)
    Synonyms
    aplp antibody, MGC115336 antibody, APLP antibody, Aplp1_retired antibody, RGD1561211 antibody, amyloid beta precursor like protein 1 antibody, amyloid beta precursor like protein 1 L homeolog antibody, amyloid beta (A4) precursor-like protein 1 antibody, APLP1 antibody, aplp1.L antibody, aplp1 antibody, Aplp1 antibody
    Background
    This gene encodes a member of the highly conserved amyloid precursor protein gene family. The encoded protein is a membrane-associated glycoprotein that is cleaved by secretases in a manner similar to amyloid beta A4 precursor protein cleavage. This cleavage liberates an intracellular cytoplasmic fragment that may act as a transcriptional activator. The encoded protein may also play a role in synaptic maturation during cortical development. Alternatively spliced transcript variants encoding different isoforms have been described.
    Molecular Weight

    Observed_MW: 65-70 kDa

    Calculated_MW: 72 kDa

    Gene ID
    333
    UniProt
    P51693
    Pathways
    cAMP Metabolic Process
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